Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 5/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824305 | 0.93 | MAPK14 (0.48) | MEN1KMT2AMAPK14 | |
| SCHEMBL6820704 | 0.81 | CDK1 (0.59) | MEN1KMT2AMAPK14KIT | |
| SCHEMBL7064551 | 0.81 | ADORA2A (0.41) | ATRMEN1KMT2A | |
| SCHEMBL6821420 | 0.79 | CDK1 (0.43) | MEN1KMT2AMAPK14 | |
| SCHEMBL6824731 | 0.79 | ALDH1A1 (0.39) | MEN1KMT2A | |
| SCHEMBL6821385 | 0.78 | MAPK14 (0.34) | MAPK14KIT | |
| SCHEMBL6823630 | 0.78 | CDK1 (0.49) | — | |
| SCHEMBL6923124 | 0.78 | CDK1 (0.53) | KMT2AMAPK14 | |
| SCHEMBL6824771 | 0.78 | CDK1 (0.38) | IKBKBMEN1KMT2A | |
| SCHEMBL6823887 | 0.77 | CDK2 (0.37) | MEN1KMT2AMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004080979-A1 | NOVEL 3-(2-AMINO-4-PYRIMIDINYL)-4-HYDROXYPHENYL KETONE DERIVATIVES | LG LIFE SCIENCES LTD. (KR) | 2004-09-23 | — | — | WO | claimed |
| WO-2004080979-A1 | NOVEL 3-(2-AMINO-4-PYRIMIDINYL)-4-HYDROXYPHENYL KETONE DERIVATIVES | LG LIFE SCIENCES LTD. (KR) | 2004-09-23 | — | — | WO | disclosed |