Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | ROS1 | P08922 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820704 | 0.95 | CDK1 (0.59) | CDK1CDK2ALDH1A1HTTKMT2A | |
| SCHEMBL6821420 | 0.92 | CDK1 (0.43) | CDK1CDK2KMT2AMAPK14KDR | |
| SCHEMBL6824812 | 0.86 | CDK1 (0.39) | CDK1CDK2ALDH1A1KMT2AMAPT | |
| SCHEMBL6824305 | 0.85 | MAPK14 (0.48) | CDK1CDK2ALDH1A1HTTKMT2A | |
| SCHEMBL6826271 | 0.85 | KDM4E (0.41) | CDK1CDK2ALDH1A1MAPK14SMN1; SMN2 | |
| SCHEMBL6824355 | 0.85 | CDK1 (0.42) | CDK1CDK2ALDH1A1L3MBTL1MAPK14 | |
| SCHEMBL6826381 | 0.84 | MAPK14 (0.39) | CDK1CDK2ALDH1A1HTTKMT2A | |
| SCHEMBL6824848 | 0.84 | CACNA1G (0.43) | CDK1CDK2NPC1RAB9A | |
| SCHEMBL6824771 | 0.84 | CDK1 (0.38) | CDK1CDK2ALDH1A1KMT2AKDR | |
| SCHEMBL6824329 | 0.83 | HTT (0.36) | CDK1CDK2ALDH1A1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004080979-A1 | NOVEL 3-(2-AMINO-4-PYRIMIDINYL)-4-HYDROXYPHENYL KETONE DERIVATIVES | LG LIFE SCIENCES LTD. (KR) | 2004-09-23 | — | — | WO | claimed |
| WO-2004080979-A1 | NOVEL 3-(2-AMINO-4-PYRIMIDINYL)-4-HYDROXYPHENYL KETONE DERIVATIVES | LG LIFE SCIENCES LTD. (KR) | 2004-09-23 | — | — | WO | disclosed |