Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 10/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.56 |
| ▸ | DPP4 | P27487 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.56 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.56 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.56 |
| ▸ | GAPDH | P04406 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.56 |
| ▸ | STAT6 | P42226 | 1/20 | 0.56 |
| ▸ | PI4KA | P42356 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.56 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.56 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.56 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735071 | 0.89 | AHCY (0.58) | AHCYADORA3ADORA2BADORA2ADPP4 | |
| SCHEMBL226039 | 0.86 | AHCY (0.63) | AHCYADORA3ADORA2BADORA2ADPP4 | |
| SCHEMBL15643454 | 0.85 | PRMT5 (0.63) | AHCYADORA3ADORA2BADORA2ADPP4 | |
| SCHEMBL397800 | 0.83 | AHCY (0.68) | AHCYADORA3ADORA2BADORA2ADPP4 | |
| SCHEMBL31680251 | 0.83 | AHCY (0.68) | AHCYADORA3ADORA2BADORA2ADPP4 | |
| SCHEMBL11134096 | 0.82 | AHCY (0.64) | AHCYADORA3ADORA2BADORA2ADPP4 | |
| SCHEMBL18520788 | 0.82 | PRMT5 (0.64) | AHCYADORA3ADORA2BADORA2ADPP4 | |
| SCHEMBL21413837 | 0.82 | PRMT5 (0.64) | AHCYADORA3ADORA2BADORA2ADPP4 | |
| SCHEMBL13173634 | 0.82 | PRMT5 (0.64) | AHCYADORA3ADORA2BADORA2ADPP4 | |
| SCHEMBL22326785 | 0.82 | PRMT5 (0.64) | AHCYADORA3ADORA2BADORA2ADPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6740644-B2 | ADENOSINE DERIVATIVES, AGONISTS AT THE ADENOSINE A1 RECEPTOR | SMITHKLINE BEECHAM CORPORATION | 2004-05-25 | — | — | US | claimed |