Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 4/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6839267 | 0.85 | PTPRZ1 (0.41) | PTPRZ1PTPN1ALDH1A1KDM4ETDP1 | |
| SCHEMBL6821381 | 0.84 | PTPRZ1 (0.41) | PTPRZ1PTPN1ALDH1A1KDM4ETDP1 | |
| SCHEMBL6821379 | 0.84 | PTPRZ1 (0.41) | PTPRZ1PTPN1ALDH1A1KDM4ETDP1 | |
| SCHEMBL6824238 | 0.81 | SLC6A4 (0.41) | ALDH1A1KDM4EHTT | |
| SCHEMBL4714463 | 0.80 | PTPRZ1 (0.45) | PTPRZ1PTPN1ALDH1A1KDM4ETDP1 | |
| SCHEMBL6835174 | 0.80 | TAAR1 (0.38) | ALDH1A1KDM4E | |
| SCHEMBL6839306 | 0.79 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL6839460 | 0.78 | MCL1 (0.34) | ALDH1A1KDM4EHTTATM | |
| SCHEMBL4657617 | 0.77 | PTPRZ1 (0.41) | PTPRZ1PTPN1ALDH1A1KDM4ETDP1 | |
| SCHEMBL6841637 | 0.76 | ALDH1A1 (0.36) | ALDH1A1TDP1EPHX2NR1H4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142821-A1 | Pesticide composition comprising malononitrile compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-07-22 | — | — | US | disclosed |
| EP-1385377-A1 | PESTICIDE COMPOSITION COMPRISING MALONONITRILE COMPOUNDS | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002089579-A1 | PESTICIDE COMPOSITION COMPRISING MALONONITRILE COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142821-A1 | Pesticide composition comprising malononitrile compounds | CBR1, CBR3, ME1 | PTPRZ1 2274/4885PTPN1 1245/4885ALDH1A1 867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.