Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | NPY4R | P50391 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.44 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.44 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.43 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.42 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.42 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824254 | 1.00 | LNPEP (0.47) | LNPEPERAP2NPY1RNPY2RNPY4R | |
| SCHEMBL4906337 | 0.96 | NPY1R (0.50) | LNPEPERAP2NPY1RNPY2RNPY4R | |
| SCHEMBL4906380 | 0.96 | NPY1R (0.50) | LNPEPERAP2NPY1RNPY2RNPY4R | |
| SCHEMBL30309257 | 0.94 | LNPEP (0.52) | LNPEPERAP2NPY1RNPY2RNPY4R | |
| SCHEMBL30575101 | 0.92 | NPY1R (0.49) | LNPEPERAP2NPY1RNPY2RNPY4R | |
| SCHEMBL29540760 | 0.92 | GHSR (0.49) | — | |
| SCHEMBL30081066 | 0.91 | NPY1R (0.49) | LNPEPERAP2NPY1RNPY2RNPY4R | |
| SCHEMBL29540123 | 0.91 | NPY1R (0.49) | LNPEPERAP2NPY1RNPY2RNPY4R | |
| SCHEMBL30592737 | 0.91 | NPY1R (0.49) | LNPEPERAP2NPY1RNPY2RNPY4R | |
| SCHEMBL29462006 | 0.90 | GHSR (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6737515-B2 | GENETIC ENGINEERING | WASHINGTON UNIVERSITY | 2004-05-18 | — | — | US | disclosed |
| US-6306654-B1 | NUCLEOTIDE SEQUENCE CODING MUTANT GONADOTROPHIN HORMONE; FOR TREATMENT OF REPRODUCTION DEFECTS | WASHINGTON UNIVERSITY | 2001-10-23 | — | — | US | disclosed |
| US-20010007757-A1 | Follicle stimulating hormone-glycosylation analogs | BOIME IRVING (US) | 2001-07-12 | — | — | US | disclosed |
| US-5712122-A | Carboxy terminal peptide-extended proteins | WASHINGTON UNIVERSITY (US) | 1998-01-27 | — | — | US | disclosed |
| EP-0461200-B1 | MODIFIED FORMS OF REPRODUCTIVE HORMONES | UNIV WASHINGTON (US) | 1997-01-22 | — | — | EP | disclosed |
| US-5585345-A | CARBOXY TERMINAL PEPTIDES | WASHINGTON UNIVERSITY (US) | 1996-12-17 | — | — | US | disclosed |
| US-5405945-A | Genetic engineering | WASHINGTON UNIVERSITY (US) | 1995-04-11 | — | — | US | disclosed |
| US-5338835-A | Mutant forms with unique glycosylation patterns | WASHINGTON UNIVERSITY (US) | 1994-08-16 | — | — | US | disclosed |
| US-5177193-A | In vivo half-life, genetic engineering | WASHINGTON UNIVERSITY (US) | 1993-01-05 | — | — | US | disclosed |
| EP-0461200-A4 | MODIFIED FORMS OF REPRODUCTIVE HORMONES | — | 1992-11-19 | — | — | EP | disclosed |
| EP-0461200-A1 | MODIFIED FORMS OF REPRODUCTIVE HORMONES. | UNIV WASHINGTON (US) | 1991-12-18 | — | — | EP | disclosed |
| WO-1990009800-A1 | MODIFIED FORMS OF REPRODUCTIVE HORMONES | WASHINGTON UNIVERSITY (US) | 1990-09-07 | — | — | WO | disclosed |