SCHEMBL6824286

SCHEMBL6824286

CCCCC(C)Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CSNK1E P49674 1/20 0.49
SIGMAR1 Q99720 5/20 0.48
TAAR1 Q96RJ0 4/20 0.48
SLC6A2 P23975 2/20 0.48
MAOA P21397 1/20 0.48
SLC6A4 P31645 1/20 0.48
SLC6A3 Q01959 1/20 0.48
CYP2A6 P11509 1/20 0.48
ADORA2A P29274 1/20 0.48
ADORA1 P30542 1/20 0.48
CTSK P43235 2/20 0.46
TRPA1 O75762 2/20 0.46
CTSL P07711 1/20 0.46
CTSB P07858 1/20 0.46
CTSH P09668 1/20 0.46
SLC18A2 Q05940 1/20 0.45
CYP2D6 P10635 1/20 0.45
CNR2 P34972 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6693090 0.94 CSNK1E (0.56) CSNK1ESIGMAR1TAAR1SLC6A2MAOA
SCHEMBL16752540 0.92 CSNK1E (0.58) CSNK1ESIGMAR1TAAR1SLC6A2MAOA
SCHEMBL16752543 0.92 CSNK1E (0.58) CSNK1ESIGMAR1TAAR1SLC6A2MAOA
SCHEMBL16752541 0.92 CSNK1E (0.58) CSNK1ESIGMAR1TAAR1SLC6A2MAOA
SCHEMBL25212657 0.92 CSNK1E (0.58) CSNK1ESIGMAR1TAAR1SLC6A2MAOA
SCHEMBL25204172 0.92 CSNK1E (0.58) CSNK1ESIGMAR1TAAR1SLC6A2MAOA
SCHEMBL9242565 0.92 CSNK1E (0.58) CSNK1ESIGMAR1TAAR1SLC6A2MAOA
SCHEMBL16370367 0.92 CSNK1E (0.58) CSNK1ESIGMAR1TAAR1SLC6A2MAOA
SCHEMBL6060574 0.92 CSNK1E (0.58) CSNK1ESIGMAR1TAAR1SLC6A2MAOA
SCHEMBL5678132 0.92 CSNK1E (0.58) CSNK1ESIGMAR1TAAR1SLC6A2MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111727215-B Antioxidant-containing methane-forming crosslinking composition and articles thereof 博里利斯股份公司 2022-08-09 CN disclosed
US-10808246-B2 Oligonucleotide-ligand conjugates and process for their preparation ALNYLAM PHARMACEUTICALS, INC. (US) 2020-10-20 US disclosed
CN-108368296-B High transparency melt polymerized polycarbonate with improved impact properties 沙特基础工业全球技术公司 2020-07-03 CN disclosed
CN-110746341-A Method for purifying 2-aryl-3, 3-bis (4-hydroxyaryl) phthalimidines and polymers derived therefrom 沙特基础工业全球技术有限公司 2020-02-04 CN disclosed
EP-3131965-A1 METHODS OF PREPARING COMPOSITIONS FOR CONTAINERS AND OTHER ARTICLES AND METHODS OF USING SAME Valspar Sourcing, Inc. (US) 2017-02-22 EP disclosed
US-20160376585-A1 OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION BANK OF AMERICA, N.A. 2016-12-29 US disclosed
CN-106063946-A Absorbability oxidized cellulose thromboembolism forms solution 柯惠LP公司 2016-11-02 CN disclosed
EP-3019200-A2 OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION Alnylam Pharmaceuticals, Inc. (US) 2016-05-18 EP disclosed
WO-2015160788-A1 METHODS OF PREPARING COMPOSITIONS FOR CONTAINERS AND OTHER ARTICLES AND METHODS OF USING SAME VALSPAR SOURCING, INC. (US) 2015-10-22 WO disclosed
EP-2882818-A1 STABILIZER AND COATING COMPOSITIONS THEREOF Valspar Sourcing, Inc. (US) 2015-06-17 EP disclosed
WO-2014025411-A1 CONTAINER COATING SYSTEM VALSPAR SOURCING, INC. (US) 2014-02-13 WO disclosed
WO-2014025410-A1 STABILIZER AND COATING COMPOSITIONS THEREOF VALSPAR SOURCING, INC. (US) 2014-02-13 WO disclosed
WO-2014025406-A1 DENTAL MATERIALS AND METHOD OF MANUFACTURE VALSPAR SOURCING, INC. (US) 2014-02-13 WO disclosed
WO-2014025400-A1 DEVELOPER FOR THERMALLY RESPONSIVE RECORD MATERIALS VALSPAR SOURCING, INC. (US) 2014-02-13 WO disclosed
EP-1379602-A1 PROCESS FOR THE MANUFACTURE OF TEMPERATURE-SENSITIVE POLYMERS Solutia Inc. (US) 2004-01-14 EP disclosed
WO-2002083812-A1 PROCESS FOR THE MANUFACTURE OF TEMPERATURE-SENSITIVE POLYMERS SOLUTIA INC. (US) 2002-10-24 WO disclosed
US-4351945-A Two-phase process for the preparation of azole and azoline disulfides EXXON RESEARCH & ENGINEERING CO. (US) 1982-09-28 US disclosed
US-4155910-A OXIDATIVE COUPLING EXXON RESEARCH & ENGINEERING CO. (US) 1979-05-22 US disclosed
US-4064139-A TRANQUILIZERS, ANTICONVULSANTS, MUSCLE RELAXANTS, ANTI-PARKINSON'S DISEASE MERCK & CO., INC. (US) 1977-12-20 US disclosed
US-4039552-A CORROSION INHIBITION, WEAR RESISTANCE EXXON RESEARCH AND ENGINEERING COMPANY (US) 1977-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160376585-A1 OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION IGF2R, IRS1, INSR CSNK1E 3973/4885SIGMAR1 4432/4885TAAR1 2713/4885
US-10808246-B2 Oligonucleotide-ligand conjugates and process for their preparation RTCB, IGF2BP2, SNRPE CSNK1E 2323/4885SIGMAR1 1320/4885TAAR1 2910/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.