Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 9/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL423103 | 0.97 | GRM5 (0.48) | GRM5HPGDKMT2AMEN1TSHR | |
| SCHEMBL1427046 | 0.84 | MEN1 (0.59) | GRM5HPGDKMT2AMEN1TSHR | |
| SCHEMBL423467 | 0.81 | KMT2A (0.59) | GRM5HPGDKMT2AMEN1TSHR | |
| SCHEMBL6821163 | 0.80 | HPGD (0.49) | GRM5HPGDKMT2ATSHRCNR1 | |
| SCHEMBL23675259 | 0.80 | HPGD (0.52) | GRM5HPGDTSHRHSD11B1CNR1 | |
| SCHEMBL29994736 | 0.80 | HPGD (0.52) | GRM5HPGDTSHRHSD11B1CNR1 | |
| SCHEMBL990157 | 0.80 | GRM5 (0.64) | GRM5HPGDKMT2AMEN1 | |
| SCHEMBL20577446 | 0.76 | GRM5 (0.54) | GRM5HPGDHSD11B1CNR1 | |
| SCHEMBL13433926 | 0.76 | HPGD (0.55) | GRM5HPGDMAPK1 | |
| SCHEMBL427869 | 0.74 | HCAR2 (0.47) | KMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074278-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-09-02 | — | — | WO | disclosed |