Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 3/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1187879 | 0.84 | DHODH (0.52) | HPGDDHODHKMT2ALMNATP53 | |
| SCHEMBL6824364 | 0.80 | GRM5 (0.51) | HPGDTSHRGRM5KMT2AMAPK1 | |
| SCHEMBL22096781 | 0.80 | CHRNB2 (0.45) | DHODHLMNATP53MAPT | |
| SCHEMBL2366247 | 0.79 | KDM4E (0.42) | HPGDTSHRKMT2ALMNATP53 | |
| SCHEMBL423103 | 0.77 | GRM5 (0.48) | HPGDTSHRGRM5KMT2ALMNA | |
| SCHEMBL2365753 | 0.75 | MEN1 (0.43) | KMT2AMAPT | |
| SCHEMBL13433926 | 0.75 | HPGD (0.55) | HPGDGRM5MAPK1ALDH1A1KDM4E | |
| SCHEMBL10306678 | 0.75 | TSHR (0.40) | TSHRKMT2AHSD17B10 | |
| SCHEMBL2366420 | 0.74 | KDM4E (0.38) | HPGDTSHRTP53ALDH1A1KDM4E | |
| SCHEMBL2366878 | 0.74 | ALDH1A1 (0.38) | HPGDTSHRKMT2AMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074278-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-09-02 | — | — | WO | disclosed |