Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.73 |
| ▸ | GLO1 | Q04760 | 5/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6827186 | 1.00 | L3MBTL1 (0.73) | L3MBTL1GLO1HSP90AA1GABRA1GABRG2 | |
| SCHEMBL6827244 | 0.80 | L3MBTL1 (0.81) | L3MBTL1GLO1HSP90AA1 | |
| SCHEMBL6824832 | 0.80 | L3MBTL1 (0.81) | L3MBTL1GLO1HSP90AA1 | |
| SCHEMBL6826999 | 0.78 | L3MBTL1 (0.76) | L3MBTL1GLO1HSP90AA1 | |
| SCHEMBL6827138 | 0.78 | L3MBTL1 (0.76) | L3MBTL1GLO1HSP90AA1 | |
| SCHEMBL6827252 | 0.77 | L3MBTL1 (0.73) | L3MBTL1GLO1HSP90AA1KDM4EHPGD | |
| SCHEMBL13682562 | 0.75 | TSHR (0.59) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL6824235 | 0.74 | L3MBTL1 (0.65) | L3MBTL1GLO1KDM4EHPGD | |
| SCHEMBL72569 | 0.73 | TSHR (0.68) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| Water SCHEMBL6336152 | 0.73 | TSHR (0.68) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | claimed |
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |