Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.76 |
| ▸ | GLO1 | Q04760 | 4/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | DHODH | Q02127 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826999 | 1.00 | L3MBTL1 (0.76) | L3MBTL1GLO1EGFRDHODHHSP90AA1 | |
| SCHEMBL6827244 | 0.81 | L3MBTL1 (0.81) | L3MBTL1GLO1HSP90AA1MAPTHTT | |
| SCHEMBL6824832 | 0.81 | L3MBTL1 (0.81) | L3MBTL1GLO1HSP90AA1MAPTHTT | |
| SCHEMBL6827186 | 0.78 | L3MBTL1 (0.73) | L3MBTL1GLO1HSP90AA1 | |
| SCHEMBL6827252 | 0.78 | L3MBTL1 (0.73) | L3MBTL1GLO1HSP90AA1ALDH1A1HTT | |
| SCHEMBL6824466 | 0.78 | L3MBTL1 (0.73) | L3MBTL1GLO1HSP90AA1 | |
| SCHEMBL18419413 | 0.76 | EGFR (0.84) | EGFRDHODHMKNK1MKNK2RXRA | |
| SCHEMBL17014856 | 0.76 | EGFR (0.84) | EGFRDHODHMKNK1MKNK2RXRA | |
| SCHEMBL30610335 | 0.76 | EGFR (0.84) | EGFRDHODHMKNK1MKNK2RXRA | |
| Hydrazine SCHEMBL28280116 | 0.74 | EGFR (0.67) | EGFRDHODHMKNK1MKNK2MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | claimed |
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |