Gardenoside

SCHEMBL6824467

COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]2[C@@H]1C=C[C@@]2(O)CO.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	POLB	P06746	1/20	0.78

▸	CTDSP1	Q9GZU7	1/20	0.78

▸	STAT3	P40763	13/20	0.44

▸	MEN1	O00255	1/20	0.44

▸	MAPT	P10636	1/20	0.44

▸	KMT2A	Q03164	1/20	0.44

▸	JUN	P05412	2/20	0.43

▸	ELANE	P08246	1/20	0.43

▸	HTR1A	P08908	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Galioside SCHEMBL29431810	0.88	POLB (1.00)	POLBCTDSP1STAT3MEN1MAPT
Gardenoside SCHEMBL306407	0.88	POLB (1.00)	POLBCTDSP1STAT3MEN1MAPT
SCHEMBL422338	0.79	POLB (0.80)	POLBCTDSP1STAT3MEN1MAPT
SCHEMBL422339	0.79	POLB (0.80)	POLBCTDSP1STAT3MEN1MAPT
Loganin SCHEMBL6821223	0.77	STAT3 (0.77)	STAT3MEN1MAPTKMT2A
Trehalose SCHEMBL3727947	0.74	PTPN1 (0.41)	STAT3MEN1MAPTKMT2A
Trehalose SCHEMBL404247	0.74	PTPN1 (0.41)	STAT3MEN1MAPTKMT2A
Trehalose SCHEMBL8413279	0.74	PTPN1 (0.41)	STAT3MEN1MAPTKMT2A
Trehalose SCHEMBL10381940	0.73	PTPN1 (0.40)	STAT3MEN1MAPTKMT2A
SCHEMBL29425976	0.73	POLB (0.70)	POLBCTDSP1STAT3MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2004089926-A2	GENIPIN DERIVATIVES AND USES THEREOF	BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US)	2004-10-21	—	—	WO	disclosed