SCHEMBL422338

SCHEMBL422338

O=C(O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C2[C@@H]1C=C[C@]2(O)CO

nearest known ligand 0.80

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.80
▸ CTDSP1 Q9GZU7 1/20 0.80
▸ MAPT P10636 2/20 0.52
▸ STAT3 P40763 7/20 0.43
▸ MEN1 O00255 2/20 0.43
▸ KMT2A Q03164 2/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ GLA P06280 1/20 0.43
▸ CYP3A4 P08684 1/20 0.43
▸ HSP90AA1 P07900 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL422339 1.00 POLB (0.80) POLBCTDSP1MAPTSTAT3MEN1
Gardenoside SCHEMBL306407 0.89 POLB (1.00) POLBCTDSP1MAPTSTAT3MEN1
Galioside SCHEMBL29431810 0.89 POLB (1.00) POLBCTDSP1MAPTSTAT3MEN1
Fluorouracil SCHEMBL23495449 0.88 POLB (0.63) POLBCTDSP1MAPTSTAT3MEN1
SCHEMBL29426021 0.81 POLB (0.69) POLBCTDSP1HSP90AA1
SCHEMBL29751499 0.81 POLB (0.57) POLBCTDSP1MAPTKDM4EGLA
Pelargonidin SCHEMBL6072597 0.81 POLB (0.57) POLBCTDSP1MAPTKDM4EHSP90AA1
Gardenoside SCHEMBL6824467 0.79 POLB (0.78) POLBCTDSP1MAPTSTAT3MEN1
SCHEMBL29425733 0.77 MAPT (0.56) POLBCTDSP1MAPTSTAT3MEN1
Shanzhiside SCHEMBL306203 0.75 MAPT (0.58) POLBCTDSP1MAPTSTAT3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4615506-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES Sahin, Fikret (TR) 2025-09-17 — — EP claimed
WO-2024258363-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES SAHIN FIKRET (TR) 2024-12-19 — — WO claimed
US-20240350574-A1 PHENOLIC PHYTOCHEMICALS FOR BONE METASTASIS OF CANCER NDSU RESEARCH FOUNDATION 2024-10-24 — — US claimed
CN-115702903-A Application of monotropein in promoting fracture healing 上海中医药大学附属龙华医院 2023-02-17 — — CN claimed
CN-115414373-A Application of monotropein in preparation of medicine for treating cardiovascular diseases 四川大学华西医院 2022-12-02 — — CN claimed
CN-113730467-B Medicinal composition for treating coronary heart disease and preparation method thereof 周至年青保制药有限公司 2022-09-09 — — CN claimed
CN-114965808-A A control extract of Morinda citrifolia granule and its preparation method 广州科曼生物科技有限公司 2022-08-30 — — CN claimed
CN-114732841-A Medicinal extract for preventing and treating diabetes and application thereof 中国科学院昆明植物研究所 2022-07-12 — — CN claimed
CN-114324726-A Thin-layer chromatography detection method of kidney nourishing and fetus culturing pills 广州白云山中一药业有限公司 2022-04-12 — — CN claimed
CN-112592846-B Process for preparing chemical raw materials by recycling kitchen waste 浙江海洋大学 2021-12-28 — — CN claimed
WO-2018106002-A1 COMPOSITION FOR PREVENTING AND TREATING MALE INFERTILITY, CONTAINING COMPOUND COMBINATION COMPRISING FLAVONOID DERIVATIVE AND IRIDOID DERIVATIVE AS ACTIVE INGREDIENT, AND USE THEREOF 전북대학교 산학협력단 2018-06-14 — — WO claimed
WO-2018105999-A1 COMPOSITION FOR PREVENTING AND TREATING MALE INFERTILITY, CONTAINING IRIDOID DERIVATIVE COMPOUND AS ACTIVE INGREDIENT, AND USE THEREOF 전북대학교 산학협력단 2018-06-14 — — WO claimed
CN-107802634-A A kind of pharmaceutical composition for treating Alzheimer syndrome and its application 新乡医学院 2018-03-16 — — CN claimed
CN-106668051-A Pharmaceutical composition for treating atherosclerosis and application thereof 新乡医学院 2017-05-17 — — CN claimed
CN-106386371-A Management method for pollution-free grape 合肥市田然农业科技园有限公司 2017-02-15 — — CN claimed
CN-104311612-B The method separating Monotropein is extracted from Radix Morindae Officinalis 桂林三宝药业有限公司 2016-08-24 — — CN claimed
US-20160220625-A1 METHOD FOR ENHANCED PRODUCTION OF MORINDA METABOLITES CHAN SHAM YUEN (US) 2016-08-04 — — US claimed
CN-105748655-A Method for enhanced production of morinda metabolites 陈深源 2016-07-13 — — CN claimed
CN-104311612-A Method for extracting and separating monotropein from radix morindae officinalis GUILIN SANBAO PHARMACEUTICAL CO LTD 2015-01-28 — — CN claimed
CN-101874841-A Total glycosides extractive of morinda plants, as well as preparation method and application thereof CHEN XIAOHUI 2010-11-03 — — CN claimed
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