Trehalose

Trehalose

SCHEMBL404247

O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OC[C@H]1O[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 2/20 0.41
▸ L3MBTL1 Q9Y468 2/20 0.40
▸ MEN1 O00255 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ SYNJ2 O15056 1/20 0.37
▸ LGALS8 O00214 1/20 0.36
▸ LGALS3 P17931 1/20 0.36
▸ LGALS4 P56470 1/20 0.36
▸ CETP P11597 1/20 0.36
▸ GAA P10253 1/20 0.36
▸ TYR P14679 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ STAT3 P40763 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trehalose SCHEMBL3727947 1.00 PTPN1 (0.41) PTPN1L3MBTL1MEN1KMT2ASYNJ2
Trehalose SCHEMBL8413279 1.00 PTPN1 (0.41) PTPN1L3MBTL1MEN1KMT2ASYNJ2
Trehalose SCHEMBL10381940 0.99 PTPN1 (0.40) PTPN1L3MBTL1MEN1KMT2ASYNJ2
Trehalose SCHEMBL8345963 0.91 LGALS8 (0.43) MEN1KMT2ALGALS8LGALS3LGALS4
Demannose SCHEMBL2637762 0.90 MEN1 (0.40) PTPN1L3MBTL1MEN1KMT2ALGALS8
Maltitol SCHEMBL15271873 0.90 L3MBTL1 (0.36) PTPN1L3MBTL1MEN1KMT2ASYNJ2
Cellobiose SCHEMBL23699869 0.89 LGALS8 (0.44) MEN1KMT2ALGALS8LGALS3LGALS4
Demannose SCHEMBL8488325 0.89 LGALS8 (0.44) MEN1KMT2ALGALS8LGALS3LGALS4
Cellobiose SCHEMBL17941750 0.89 LGALS8 (0.44) MEN1KMT2ALGALS8LGALS3LGALS4
Maltose SCHEMBL537670 0.89 LGALS8 (0.44) MEN1KMT2ALGALS8LGALS3LGALS4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4221778-A1 MATRICES FOR SELECTIVE BINDING OF AT LEAST ONE COMPONENT FROM A BODY FLUID Alteco Medical AB (SE) 2023-08-09 — — EP claimed
CN-103450288-B A kind of isolation and purification method of trehalose QILU UNIVERSITY OF TECHNOLOGY (CN) 2016-05-11 — — CN claimed
CN-103450288-A Separation and purification method of trehalose UNIV QILU TECHNOLOGY 2013-12-18 — — CN claimed
EP-0160743-B1 MINIATURIZED YEAST IDENTIFICATION SYSTEM Wadley Technologies, Inc. (US) 1989-03-22 — — EP claimed
US-20210299093-A1 PROPHYLACTIC OR THERAPEUTIC AGENT FOR PULMONARY HYPERTENSION COMPRISING UNSATURATED 5-MEMBERED HETEROCYCLE-CONTAINING COMPOUND TOHOKU UNIVERSITY (JP) 2021-09-30 — — US disclosed
CN-112839524-A Insect feed 嘉吉公司 2021-05-25 — — CN disclosed
CN-110506111-A Trehalose phosphorylase C LECTA GMBH 2019-11-26 — — CN disclosed
CN-108779501-A powder containing α, α -trehalose dihydrate crystal, method for producing same, and use thereof 株式会社林原 2018-11-09 — — CN disclosed
CN-105418694-B A kind of preparation method of trehalose 廊坊梅花生物技术开发有限公司 2018-07-17 — — CN disclosed
CN-103450288-B A kind of isolation and purification method of trehalose QILU UNIVERSITY OF TECHNOLOGY (CN) 2016-05-11 — — CN disclosed
CN-103450288-B A kind of isolation and purification method of trehalose QILU UNIVERSITY OF TECHNOLOGY (CN) 2016-05-11 — — CN disclosed
CN-105418694-A Preparation method of trehalose LANGFANG MEIHUA BIO-TECHNOLOGY DEV CO LTD 2016-03-23 — — CN disclosed
US-5716838-A CULTURE OF MICROORGANISMS SUCH AS RHIZOBIUM, ARTHROBACTER KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 1998-02-10 — — US disclosed
WO-1997042980-A1 METHODS OF TERMINAL STERILIZATION OF BIOLOGICAL PRODUCTS QUADRANT HOLDINGS CAMBRIDGE LIMITED (GB) 1997-11-20 — — WO disclosed
US-5681826-A INCLUDES A SUGAR ALCOHOL AND A NON-REDUCING SACCHARIDE CONTAINING TREHALOSE KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 1997-10-28 — — US disclosed
US-5677442-A CRYSTALLIZING FROM CONCENTRATED AQUEOUS SOLUTION KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 1997-10-14 — — US disclosed
US-5610047-A TREHALOSE KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 1997-03-11 — — US disclosed
US-5455168-A Production of non-reducing saccharides KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 1995-10-03 — — US disclosed
CN-1105067-A Non-reducing saccharide-forming enzyme, preparation and use thereof HAYASHIBARA BIOCHEM LAB (JP) 1995-07-12 — — CN disclosed
CN-1091470-A Unreductases produced of saccharide and preparation thereof and application HAYASHIHARA BIOCHEMICAL INST C (JP) 1994-08-31 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210299093-A1 PROPHYLACTIC OR THERAPEUTIC AGENT FOR PULMONARY HYPERTENSION COMPRISING UNSATURATED 5-MEMBERED HETEROCYCLE-CONTAINING COMPOUND PTGIR, AGTR1, SHROOM3 PTPN1 4126/4885L3MBTL1 2992/4885MEN1 1704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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