Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1600461 | 0.83 | ALDH1A1 (1.00) | ALDH1A1POLBTSHRCYP3A4CYP2C19 | |
| SCHEMBL13183093 | 0.81 | ALDH1A1 (0.70) | ALDH1A1TSHRCYP3A4L3MBTL1USP2 | |
| SCHEMBL151627 | 0.80 | ALDH1A1 (0.52) | ALDH1A1POLBGAAARTSHR | |
| SCHEMBL716384 | 0.80 | ALDH1A1 (0.52) | ALDH1A1POLBGAAARTSHR | |
| SCHEMBL153688 | 0.77 | CARM1 (0.58) | ALDH1A1POLBGAATSHRCYP3A4 | |
| SCHEMBL3447977 | 0.76 | ALDH1A1 (0.76) | ALDH1A1TSHRCYP3A4CYP2C19L3MBTL1 | |
| SCHEMBL3520495 | 0.76 | POLB (0.48) | ALDH1A1POLBGAAAR | |
| SCHEMBL10932148 | 0.76 | TSHR (0.53) | ALDH1A1POLBGAATSHRCYP2C19 | |
| SCHEMBL10962715 | 0.74 | POLB (0.47) | ALDH1A1POLBGAAAR | |
| SCHEMBL148920 | 0.74 | MAOB (0.49) | ALDH1A1POLBGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004009559-A2 | DIHYDROURACIL COMPOUNDS AS ANTI-ICTOGENIC OR ANTI-EPILEPTOGENIC AGENTS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2004-01-29 | — | — | WO | disclosed |