Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL151627 | 0.96 | ALDH1A1 (0.52) | ALDH1A1POLBGAAARTSHR | |
| SCHEMBL3520495 | 0.94 | POLB (0.48) | ALDH1A1POLBGAAAR | |
| SCHEMBL10962715 | 0.93 | POLB (0.47) | ALDH1A1POLBGAAAR | |
| SCHEMBL712716 | 0.93 | LCK (0.48) | ALDH1A1POLBGAAAR | |
| SCHEMBL713869 | 0.89 | HRH3 (0.50) | ALDH1A1POLBGAAMEN1KMT2A | |
| SCHEMBL148920 | 0.89 | MAOB (0.49) | ALDH1A1POLBGAAOPRM1TSHR | |
| SCHEMBL7877735 | 0.88 | ALDH1A1 (0.48) | ALDH1A1POLBGAAOPRM1OPRD1 | |
| SCHEMBL9016972 | 0.87 | POLB (0.46) | ALDH1A1POLBGAAARTSHR | |
| SCHEMBL13426179 | 0.87 | LCK (0.47) | ALDH1A1POLBGAA | |
| SCHEMBL17508109 | 0.86 | ALDH1A1 (0.47) | ALDH1A1POLBGAAOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0809504-B1 | ANTI-VIRAL TRIAZACYCLODODECANE | UNIV NEW YORK STATE RES FOUND (US) | 2002-05-15 | — | — | EP | claimed |
| US-20020019423-A1 | Anti-viral triaza compounds | BELL THOMAS W (US) | 2002-02-14 | — | — | US | claimed |
| US-6342492-B1 | VIRICIDES | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2002-01-29 | — | — | US | claimed |
| EP-0809504-A4 | ANTI-VIRAL TRIAZA COMPOUNDS | UNIV NEW YORK STATE RES FOUND (US) | 1998-11-04 | — | — | EP | claimed |
| EP-0809504-A1 | ANTI-VIRAL TRIAZA COMPOUNDS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1997-12-03 | — | — | EP | claimed |
| US-5663161-A | TRIAZACYCLO COMPOUNDS AS VIRICIDES | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1997-09-02 | — | — | US | claimed |
| WO-1996025167-A1 | ANTI-VIRAL TRIAZA COMPOUNDS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1996-08-22 | — | — | WO | claimed |
| US-4505861-A | Methods and intermediates for the preparation of spermidine, homospermidine and norspermidine | UNIVERSITY OF FLORIDA (US) | 1985-03-19 | — | — | US | claimed |
| US-4439380-A | Photopolymerizable composition, especially for dental purposes | ETABLISSEMENT DENTAIRE IVOCLAR (LI) | 1984-03-27 | — | — | US | claimed |
| WO-2017156177-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |
| WO-2017156177-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |
| CN-102531888-B | Chemical synthesis method of 3,4,5-trimethoxy benzoyl chloride | UNIV WENZHOU | 2014-05-14 | — | — | CN | disclosed |
| US-8354529-B2 | Polyamine derivative and polyol derivative | BASF SE (DE) | 2013-01-15 | — | — | US | disclosed |
| EP-2511274-A2 | Polyamine derivative | BASF SE (DE) | 2012-10-17 | — | — | EP | disclosed |
| US-4505861-A | Methods and intermediates for the preparation of spermidine, homospermidine and norspermidine | UNIVERSITY OF FLORIDA (US) | 1985-03-19 | — | — | US | disclosed |
| US-4439380-A | Photopolymerizable composition, especially for dental purposes | ETABLISSEMENT DENTAIRE IVOCLAR (LI) | 1984-03-27 | — | — | US | disclosed |
| EP-0021361-B1 | PROCESS FOR PREPARING PHOSPHORIC ACID PROPARGYL ESTERS | BAYER AG (DE) | 1982-10-06 | — | — | EP | disclosed |
| US-4327040-A | BASIC CATALYZED REACTION OF PROPARGYL ALCOHOL WITH A PHOSPHORIC ACID CHLORIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1982-04-27 | — | — | US | disclosed |
| EP-0030661-A2 | Insecticidal and acaricidal agents containing propargyl esters of thiono-phosphoric acids | BAYER AG (DE) | 1981-06-24 | — | — | EP | disclosed |
| EP-0021361-A1 | Process for preparing phosphoric acid propargyl esters | BAYER AG (DE) | 1981-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019423-A1 | Anti-viral triaza compounds | ZC3HAV1, MAVS, BAZ1A | ALDH1A1 1847/4885POLB 258/4885GAA 608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.