SCHEMBL6824787

SCHEMBL6824787

CCc1c(C)nc2ccccc2c1Nc1ccc(N2CCN(C)C(C)C2)cc1

nearest known ligand 0.84

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 20/20 0.84
ADRA2C P18825 20/20 0.84
ADRA2B P18089 17/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6822398 0.91 ADRA2A (1.00) ADRA2AADRA2CADRA2B
SCHEMBL6920151 0.87 ADRA2C (0.79) ADRA2AADRA2CADRA2B
SCHEMBL7123693 0.86 ADRA2A (1.00) ADRA2AADRA2CADRA2B
SCHEMBL6824949 0.85 ADRA2A (1.00) ADRA2AADRA2CADRA2B
SCHEMBL6921692 0.84 ADRA2A (0.86) ADRA2AADRA2CADRA2B
SCHEMBL6821541 0.83 ADRA2A (0.69) ADRA2AADRA2CADRA2B
SCHEMBL6922102 0.82 ADRA2A (0.92) ADRA2AADRA2CADRA2B
SCHEMBL6821552 0.82 ADRA2A (1.00) ADRA2AADRA2CADRA2B
SCHEMBL6920673 0.80 ADRA2A (1.00) ADRA2AADRA2CADRA2B
SCHEMBL6824815 0.79 ADRA2A (0.69) ADRA2AADRA2CADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004067513-A1 ANTAGONISTS FOR ALPHA-2 ADRENOCEPTORS OY JUVANTIA PHARMA LTD (FI) 2004-08-12 WO disclosed