Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | MMP14 | P50281 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9358455 | 0.91 | MAPT (0.47) | CA12CA1MMP2MMP9MMP8 | |
| SCHEMBL9358446 | 0.91 | MAPT (0.47) | CA12CA1MMP2MMP9MMP8 | |
| SCHEMBL6670391 | 0.87 | CA12 (0.51) | CA12CA1MMP2MMP9MMP8 | |
| SCHEMBL28142388 | 0.84 | ALDH1A1 (0.64) | CA12CA1MMP2MMP9MMP8 | |
| SCHEMBL6851287 | 0.83 | ALDH1A1 (0.52) | CA12CA1MMP2MMP9MMP8 | |
| SCHEMBL11612514 | 0.83 | ALDH1A1 (0.53) | CA12CA1MMP2MMP9MMP8 | |
| SCHEMBL3866264 | 0.82 | CA12 (0.57) | CA12CA1MMP2MMP9MMP8 | |
| SCHEMBL20578009 | 0.82 | MEN1 (0.53) | CA12CA1MMP2MMP9MMP8 | |
| SCHEMBL4616467 | 0.81 | MAPT (0.59) | CA12CA1MMP2MMP9MMP8 | |
| SCHEMBL11615334 | 0.81 | MAPT (0.54) | CA12CA1MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004063175-A1 | A NOVEL AND AN IMPROVED PROCESS FOR THE PREPARATION OF (S)-4-(4-AMINOBENZYL)-2- OXAZOLIDINONE | NATCO PHARMA LIMITED (IN) | 2004-07-29 | — | — | WO | disclosed |