Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | MMP8 | P22894 | 1/20 | 0.57 |
| ▸ | MMP14 | P50281 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671268 | 0.90 | MAPT (0.53) | CA12CA1MMP2MMP9MMP8 | |
| SCHEMBL6570551 | 0.90 | MAPT (0.53) | CA12CA1MMP2MMP9MMP8 | |
| SCHEMBL5127357 | 0.87 | ALDH1A1 (0.53) | CA12CA1MMP2MMP9MMP8 | |
| SCHEMBL5119014 | 0.87 | MAPT (0.50) | CA12CA1MMP2MMP9MMP8 | |
| SCHEMBL5119021 | 0.87 | MAPT (0.50) | CA12CA1MMP2MMP9MMP8 | |
| SCHEMBL5127362 | 0.87 | ALDH1A1 (0.53) | CA12CA1MMP2MMP9MMP8 | |
| SCHEMBL6003995 | 0.82 | MAPT (0.45) | CA12CA1MMP2MMP9MMP8 | |
| SCHEMBL9362332 | 0.82 | MAPT (0.45) | CA12CA1MMP2MMP9MMP8 | |
| SCHEMBL5155046 | 0.82 | ALDH1A1 (0.52) | CA12CA1MMP2MMP9MMP8 | |
| SCHEMBL6824926 | 0.82 | CA12 (0.54) | CA12CA1MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119709797-A | Broad-spectrum amidase gene aphA for degrading amidol antibiotics and amidic herbicides, and encoding protein and application thereof | 南京农业大学 | 2025-03-28 | — | — | CN | disclosed |
| EP-1948594-B1 | PROCESS FOR THE SYNTHESIS OF INTERMEDIATES OF CHLORAMPHENICOL OR ITS ANALOGUES | KRKA (SI) | 2013-02-27 | — | — | EP | disclosed |
| US-7591860-B2 | N-alkylpolyhydroxylated secondary para-phenylenediamines, dye compositions comprising them, processes, and uses thereof | L'OREAL, S.A. (FR) | 2009-09-22 | — | — | US | disclosed |
| US-7591860-B2 | N-alkylpolyhydroxylated secondary para-phenylenediamines, dye compositions comprising them, processes, and uses thereof | L'OREAL, S.A. (FR) | 2009-09-22 | — | — | US | disclosed |
| US-7591860-B2 | N-alkylpolyhydroxylated secondary para-phenylenediamines, dye compositions comprising them, processes, and uses thereof | L'OREAL, S.A. (FR) | 2009-09-22 | — | — | US | disclosed |
| US-20090149657-A1 | PROCESS FOR THE SYNTHESIS OF INTERMEDIATES OF CHLORAMPHENICOL OR ITS ANALOGUES | KRKA (SI) | 2009-06-11 | — | — | US | disclosed |
| EP-1948594-A1 | PROCESS FOR THE SYNTHESIS OF INTERMEDIATES OF CHLORAMPHENICOL OR ITS ANALOGUES | KRKA (SI) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007054147-A1 | PROCESS FOR THE SYNTHESIS OF INTERMEDIATES OF CHLORAMPHENICOL OR ITS ANALOGUES | KRKA (SI) | 2007-05-18 | — | — | WO | disclosed |
| EP-1785414-A1 | Process for the synthesis of intermediates of chloramphenicol or its analogues | KRKA, tovarna zdravil, d.d., Novo mesto (SI) | 2007-05-16 | — | — | EP | disclosed |
| US-20060026777-A1 | N-alkylpolyhydroxylated secondary para-phenylenediamines, dye compositions comprising them, processes, and uses thereof | L'OREAL S.A. (FR) | 2006-02-09 | — | — | US | disclosed |
| EP-1580184-A1 | secondary N-alkylepolyhydroxilated p-phenylendiamines, dye composition comprising them, processes and uses | L'OREAL (FR) | 2005-09-28 | — | — | EP | disclosed |
| US-20020072062-A1 | Chloramphenicol biosynthetic pathway and gene cluster | DIVERSA CORPORATION | 2002-06-13 | — | — | US | disclosed |
| EP-1203083-A1 | CHLORAMPHENICOL BIOSYNTHETIC PATHWAY AND GENE CLUSTER CHARACTERIZATION | Diversa Corporation (US) | 2002-05-08 | — | — | EP | disclosed |
| WO-2000070056-A9 | CHLORAMPHENICOL BIOSYNTHETIC PATHWAY AND GENE CLUSTER CHARACTERIZATION | DIVERSA CORP (US) | 2001-11-29 | — | — | WO | disclosed |
| WO-2000070056-A1 | CHLORAMPHENICOL BIOSYNTHETIC PATHWAY AND GENE CLUSTER CHARACTERIZATION | DIVERSA CORPORATION (US) | 2000-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060026777-A1 | N-alkylpolyhydroxylated secondary para-phenylenediamines, dye compositions comprising them, processes, and uses thereof | KRT18, CDC73, DSP | CA12 1340/4885CA1 2905/4885MMP2 1773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.