Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 14/20 | 0.64 |
| ▸ | CA1 | P00915 | 14/20 | 0.64 |
| ▸ | CA2 | P00918 | 14/20 | 0.64 |
| ▸ | CA9 | Q16790 | 14/20 | 0.64 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6827222 | 0.90 | TRPV1 (0.59) | CA12CA1CA2CA9TRPV1 | |
| SCHEMBL6824278 | 0.87 | TRPV1 (0.59) | CA12CA1CA2CA9TRPV1 | |
| SCHEMBL6821502 | 0.85 | TRPV1 (0.54) | CA12CA1CA2CA9TRPV1 | |
| SCHEMBL6822253 | 0.82 | KDM4E (0.71) | CA12CA1CA2CA9TRPV1 | |
| SCHEMBL6825453 | 0.82 | TRPV1 (0.84) | TRPV1KDM4EMEN1KMT2A | |
| SCHEMBL4196085 | 0.73 | TRPV1 (0.65) | TRPV1KDM4EALDH1A1FFAR4GPR139 | |
| SCHEMBL6825142 | 0.72 | KDM4E (0.72) | TRPV1KDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL30594489 | 0.72 | MTNR1A (0.58) | TRPV1KDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL745297 | 0.72 | MTNR1A (0.58) | TRPV1KDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL8099669 | 0.72 | KMT2A (0.58) | TRPV1KDM4EMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089881-A1 | NEW SULFONYL DERIVATIVES OF AMINONAPHTOLS | ASTRAZENECA AB (SE) | 2004-10-21 | — | — | WO | claimed |
| WO-2004089881-A1 | NEW SULFONYL DERIVATIVES OF AMINONAPHTOLS | ASTRAZENECA AB (SE) | 2004-10-21 | — | — | WO | disclosed |