Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.60 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6822253 | 0.91 | KDM4E (0.71) | KDM4EMEN1KMT2AALDH1A1TRPV1 | |
| SCHEMBL6821508 | 0.88 | KDM4E (0.67) | KDM4EMEN1KMT2AALDH1A1TRPV1 | |
| SCHEMBL6824610 | 0.85 | KDM4E (0.78) | KDM4EMEN1KMT2AALDH1A1TRPV1 | |
| SCHEMBL6827222 | 0.82 | TRPV1 (0.59) | KDM4EMEN1KMT2AALDH1A1TRPV1 | |
| SCHEMBL7247143 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TRPV1MAPTPOLB | |
| SCHEMBL7163976 | 0.77 | MTNR1A (0.43) | ALDH1A1TRPV1MAPTPOLBHTT | |
| SCHEMBL4025421 | 0.75 | TRPV1 (1.00) | KDM4EMEN1KMT2AALDH1A1TRPV1 | |
| SCHEMBL487112 | 0.73 | TRPV1 (0.44) | KDM4EMEN1KMT2AALDH1A1TRPV1 | |
| SCHEMBL6824965 | 0.72 | CA12 (0.64) | KDM4EMEN1KMT2AALDH1A1TRPV1 | |
| SCHEMBL6821502 | 0.71 | TRPV1 (0.54) | KDM4EMEN1KMT2AALDH1A1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089881-A1 | NEW SULFONYL DERIVATIVES OF AMINONAPHTOLS | ASTRAZENECA AB (SE) | 2004-10-21 | — | — | WO | claimed |
| WO-2004089881-A1 | NEW SULFONYL DERIVATIVES OF AMINONAPHTOLS | ASTRAZENECA AB (SE) | 2004-10-21 | — | — | WO | disclosed |