Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821207 | 0.87 | ALDH1A1 (0.39) | FFAR4FFAR1ALDH1A1LMNAUTS2R | |
| SCHEMBL6821517 | 0.87 | FFAR4 (0.36) | FFAR4FFAR1KITALDH1A1LMNA | |
| SCHEMBL6821531 | 0.86 | FFAR4 (0.38) | FFAR4FFAR1KITMLNRMAPT | |
| SCHEMBL6817431 | 0.85 | FFAR4 (0.51) | KDM4EFFAR4FFAR1ALDH1A1LMNA | |
| SCHEMBL6820878 | 0.84 | FFAR4 (0.52) | FFAR4FFAR1MAPTUTS2R | |
| SCHEMBL6819746 | 0.84 | FFAR4 (0.40) | FFAR4FFAR1ALDH1A1LMNAMAPK1 | |
| SCHEMBL6819870 | 0.84 | FFAR4 (0.38) | FFAR4FFAR1HSD17B1HSD17B2ALDH1A1 | |
| SCHEMBL6816212 | 0.83 | FFAR4 (0.53) | KDM4EFFAR4FFAR1ALDH1A1LMNA | |
| SCHEMBL6821259 | 0.83 | PLA2G7 (0.41) | FFAR4FFAR1ALDH1A1LMNAMAPT | |
| SCHEMBL6822143 | 0.82 | FFAR4 (0.40) | FFAR4KITLMNAMAPK1PLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043948-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |