Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823515 | 0.83 | USP2 (0.40) | USP2SMN1; SMN2GPR119RECQLATM | |
| SCHEMBL22814520 | 0.81 | USP2 (0.47) | USP2SMN1; SMN2GPR119RECQLATM | |
| SCHEMBL31283902 | 0.80 | USP2 (0.46) | USP2SMN1; SMN2GPR119RECQLATM | |
| SCHEMBL156363 | 0.78 | USP2 (0.56) | USP2SMN1; SMN2GPR119RECQLHPGD | |
| SCHEMBL6823567 | 0.76 | USP2 (0.43) | USP2SMN1; SMN2GPR119 | |
| SCHEMBL21148250 | 0.76 | USP2 (0.46) | USP2SMN1; SMN2GPR119RECQLATM | |
| SCHEMBL1700547 | 0.75 | USP2 (0.53) | USP2SMN1; SMN2GPR119RECQLHPGD | |
| SCHEMBL6823010 | 0.75 | USP2 (0.44) | USP2SMN1; SMN2GPR119RECQLEPHX2 | |
| SCHEMBL17861638 | 0.74 | USP2 (0.45) | USP2SMN1; SMN2GPR119RECQLHPGD | |
| SCHEMBL16126090 | 0.74 | USP2 (0.45) | USP2SMN1; SMN2RECQLATMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058763-A1 | 4(SPIROPIPERIDINYL)METHYL SUBSTITUTED PYRROLIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 2004-07-15 | — | — | WO | disclosed |