Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6825504 | 0.86 | TLR8 (0.43) | TLR8MCHR1IGF1RPDK2FFAR1 | |
| SCHEMBL1155842 | 0.84 | TLR8 (0.36) | TLR8MCHR1IGF1RPDK2FFAR1 | |
| SCHEMBL17153143 | 0.79 | TLR8 (0.38) | TLR8MCHR1IGF1RPDK2FFAR1 | |
| SCHEMBL13205036 | 0.79 | TLR8 (0.38) | TLR8MCHR1IGF1RPDK2FFAR1 | |
| SCHEMBL4420240 | 0.78 | TLR8 (0.34) | TLR8MCHR1IGF1R | |
| SCHEMBL12856495 | 0.78 | PDK2 (0.39) | TLR8IGF1RPDK2FFAR1 | |
| SCHEMBL4410658 | 0.76 | TLR8 (0.36) | TLR8MCHR1IGF1RPDK2 | |
| SCHEMBL13205035 | 0.76 | TLR8 (0.34) | TLR8MCHR1IGF1RPDK2FFAR1 | |
| SCHEMBL15593071 | 0.74 | ESR1 (0.40) | PDK2ENPP2 | |
| SCHEMBL16360991 | 0.74 | PDK2 (0.35) | TLR8IGF1RPDK2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7883785-B2 | 5'-mono-, 5',5''-bis- and 5',5'',5'''-tris-aryl/heteroaryl-functionalized tris-orthometallated organorhodium and organoiridium compounds; readily soluble triplet emitters | MERCK PATENT GMBH (DE) | 2011-02-08 | — | — | US | disclosed |
| US-20060127696-A1 | Rhodium and iridium complexes | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2006-06-15 | — | — | US | disclosed |