Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733471 | 0.79 | GAA (0.44) | LCKFYNCA12CA1CA2 | |
| SCHEMBL2500690 | 0.76 | ERN1 (0.50) | CYP3A4MAPTLCKFYNERN1 | |
| SCHEMBL6828149 | 0.75 | HSD17B10 (0.38) | LCKFYNCA12CA1CA2 | |
| SCHEMBL27820354 | 0.72 | LCK (0.40) | CYP3A4LCKFYNCA12CA1 | |
| SCHEMBL1856696 | 0.71 | MEN1 (0.44) | LCKFYNCA12CA1CA2 | |
| SCHEMBL6825251 | 0.71 | KDM4E (0.42) | LCKFYNAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL12689899 | 0.69 | PRKDC (0.36) | CYP3A4MAPTERN1TSHR | |
| SCHEMBL20142067 | 0.69 | GAA (0.55) | MAPTLCKFYNCA12CA1 | |
| SCHEMBL27814250 | 0.69 | KDM4E (0.50) | CYP3A4MAPTERN1MYCTDP1 | |
| SCHEMBL547627 | 0.68 | MAPT (0.44) | CYP3A4MAPTHSD17B10TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073612-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO. INC. (US) | 2004-09-02 | — | — | WO | disclosed |