Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.33 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20380155 | 0.80 | HSD17B10 (0.53) | HSD17B10TSHRLCKFYNGPR35 | |
| SCHEMBL4733471 | 0.79 | GAA (0.44) | HSD17B10TSHRLCKFYNGPR35 | |
| SCHEMBL23512536 | 0.76 | ALDH1A1 (0.34) | HSD17B10TSHRAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL6825535 | 0.75 | CYP3A4 (0.38) | HSD17B10TSHRLCKFYNGPR35 | |
| SCHEMBL6645692 | 0.75 | MEN1 (0.38) | HSD17B10TSHRLCKFYNGPR35 | |
| SCHEMBL19244712 | 0.74 | KDM4E (0.44) | HSD17B10TSHRLCKFYNPTPN1 | |
| SCHEMBL27421441 | 0.72 | KDM4E (0.45) | HSD17B10GPR35MYCKDM4EMEN1 | |
| SCHEMBL27820354 | 0.72 | LCK (0.40) | HSD17B10TSHRLCKFYNGPR35 | |
| SCHEMBL14645992 | 0.71 | KDM4E (0.42) | HSD17B10TSHRLCKFYNGPR35 | |
| SCHEMBL1856696 | 0.71 | MEN1 (0.44) | HSD17B10TSHRLCKFYNGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073612-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO. INC. (US) | 2004-09-02 | — | — | WO | disclosed |