Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.67 |
| ▸ | NPC1 | O15118 | 9/20 | 0.67 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | HPGDS | O60760 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821744 | 0.96 | RAB9A (0.72) | RAB9ANPC1MEN1KMT2AHPGDS | |
| SCHEMBL6824895 | 0.93 | RAB9A (0.77) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL28478360 | 0.82 | RAB9A (1.00) | RAB9ANPC1MEN1KMT2AHPGDS | |
| SCHEMBL2753283 | 0.78 | RAB9A (0.92) | RAB9ANPC1MEN1KMT2AHPGDS | |
| SCHEMBL4290911 | 0.78 | RAB9A (0.77) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL12443375 | 0.78 | RAB9A (1.00) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL6824475 | 0.76 | MEN1 (0.58) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL4286244 | 0.76 | RAB9A (0.72) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL24073812 | 0.75 | CYP1A2 (0.66) | RAB9ANPC1PKMCYP3A4ADORA2A | |
| SCHEMBL30142664 | 0.75 | CYP1A2 (0.66) | RAB9ANPC1PKMCYP3A4ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004099127-A1 | NOVEL COMPOUNDS AS KINASE INHIBITORS | NOVO NORDISK A/S (DK) | 2004-11-18 | — | — | WO | claimed |
| WO-2004099127-A1 | NOVEL COMPOUNDS AS KINASE INHIBITORS | NOVO NORDISK A/S (DK) | 2004-11-18 | — | — | WO | disclosed |