Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 9/20 | 0.55 |
| ▸ | CA9 | Q16790 | 9/20 | 0.55 |
| ▸ | CA1 | P00915 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GBA1 | P04062 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6825234 | 0.82 | CA9 (0.66) | SMN1; SMN2CA12CA9CA1ALDH1A1 | |
| SCHEMBL6827172 | 0.80 | CA12 (0.63) | MEN1KMT2ASMN1; SMN2CA12CA9 | |
| SCHEMBL6821744 | 0.79 | RAB9A (0.72) | MEN1KMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL6825144 | 0.79 | CA9 (0.72) | CA12CA9CA1ALDH1A1NPSR1 | |
| SCHEMBL6821696 | 0.79 | CA9 (0.64) | MEN1KMT2ASMN1; SMN2CA12CA9 | |
| SCHEMBL4816530 | 0.79 | MEN1 (0.72) | MEN1KMT2ASMN1; SMN2POLBGLA | |
| SCHEMBL6821697 | 0.77 | CA12 (0.61) | CA12CA9CA1ALDH1A1KDM4E | |
| SCHEMBL6824885 | 0.77 | CA9 (0.62) | CA12CA9CA1ALDH1A1NPSR1 | |
| SCHEMBL6825568 | 0.76 | RAB9A (0.67) | MEN1KMT2ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL6825173 | 0.75 | CA12 (0.60) | MEN1KMT2APOLBCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004099127-A1 | NOVEL COMPOUNDS AS KINASE INHIBITORS | NOVO NORDISK A/S (DK) | 2004-11-18 | — | — | WO | disclosed |