SCHEMBL6825630

SCHEMBL6825630

Cc1ccc(Sc2ccc(Sc3ccccc3C(=O)O)c3c2C(=O)c2c(Sc4ccc(C)cc4)ccc(Sc4ccccc4C(=O)O)c2C3=O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.47
ALDH1A1 P00352 3/20 0.47
RAB9A P51151 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
NPC1 O15118 2/20 0.47
GAA P10253 1/20 0.47
HSP90AA1 P07900 1/20 0.47
KDM4E B2RXH2 3/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
SIRT1 Q96EB6 1/20 0.45
NSD2 O96028 2/20 0.45
TDP1 Q9NUW8 3/20 0.45
SLC6A9 P48067 1/20 0.44
MAPT P10636 3/20 0.44
MAPK1 P28482 1/20 0.44
PKM P14618 2/20 0.43
RXFP1 Q9HBX9 1/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
CA12 O43570 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5186401 1.00 POLB (0.47) POLBALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL1775501 0.88 POLB (0.56) POLBALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL5186500 0.87 POLB (0.57) POLBALDH1A1RAB9ASMN1; SMN2KDM4E
SCHEMBL14581003 0.82 ALDH1A1 (0.45) POLBALDH1A1RAB9ASMN1; SMN2KMT2A
SCHEMBL10383781 0.81 POLB (0.51) POLBALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL6825619 0.79 MAPT (0.57) POLBALDH1A1RAB9ASMN1; SMN2KDM4E
SCHEMBL10887550 0.78 ADORA2A (0.44) POLBALDH1A1SMN1; SMN2GAAKDM4E
SCHEMBL4437794 0.77 KDM4E (0.61) POLBALDH1A1RAB9ANPC1HSP90AA1
SCHEMBL231042 0.77 SIRT1 (0.71) POLBALDH1A1RAB9ASMN1; SMN2KDM4E
SCHEMBL8531499 0.76 SIRT1 (0.56) POLBALDH1A1RAB9ASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040195552-A1 useful as powders or pellets for incorporation into a variety of thermoplastic resins; diacidic anthraquinone compounds WEAVER MAX ALLEN (US) 2004-10-07 US disclosed
US-6776930-B2 POLYMER BONDED TO DYE EASTMAN KODAK COMPANY 2004-08-17 US disclosed
US-20010023938-A1 Polymer bonded to dye ALLEN MAX (US) 2001-09-27 US disclosed
US-6197223-B1 REACTING DIACIDIC MONOMER HAVING FORMULA H--A--H, COMPRISING 1 TO 100 MOLE % OF LIGHT-ABSORBING MONOMER HAVING A LIGHT ABSORPTION MAXIMUM BETWEEN 300 NM AND 1200 NM AND 99-0 MOLE % OF A NON-LIGHT ABSORBING MONOMER WITH ORGANIC COMPOUND EASTMAN CHEMICAL COMPANY 2001-03-06 US disclosed
EP-0948570-A1 METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 1999-10-13 EP disclosed
WO-1998023690-A1 METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 1998-06-04 WO disclosed