Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24571659 | 0.74 | MEN1 (0.42) | — | |
| SCHEMBL2057335 | 0.73 | — | — | |
| SCHEMBL17358812 | 0.72 | CA1 (0.39) | CA1 | |
| SCHEMBL21422806 | 0.72 | NR1I2 (0.32) | — | |
| SCHEMBL10195803 | 0.72 | CA1 (0.39) | CA1EPHX1 | |
| SCHEMBL2715609 | 0.71 | CA1 (0.48) | CA1 | |
| Potassium Ion SCHEMBL9630756 | 0.70 | NR1I2 (0.31) | — | |
| Lithium Ion SCHEMBL28484075 | 0.70 | NR1I2 (0.31) | — | |
| SCHEMBL9631959 | 0.70 | L3MBTL1 (0.33) | — | |
| SCHEMBL10198481 | 0.70 | CA1 (0.30) | CA1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089911-A1 | PYRAZOLE DERIVATIVES AS GAMMA-SECRETASE INHIBITORS USEFUL IN THE TREATMENT OF ALZHEIMER’S DISEASE | MERCK SHARP & DOHME LIMITED (GB) | 2004-10-21 | — | — | WO | disclosed |