Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | RORA | P35398 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | RORB | Q92753 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL28484075 | 0.95 | NR1I2 (0.31) | NR1I2RORARORCRORBNR1H4 | |
| SCHEMBL9631959 | 0.95 | L3MBTL1 (0.33) | NR1I2RORARORCRORBNR1H4 | |
| Potassium Ion SCHEMBL9632525 | 0.77 | LMNA (0.32) | — | |
| Lithium Ion SCHEMBL29522617 | 0.74 | — | — | |
| Potassium Ion SCHEMBL10480413 | 0.73 | NR1I2 (0.32) | NR1I2 | |
| SCHEMBL24571659 | 0.72 | MEN1 (0.42) | — | |
| SCHEMBL9632504 | 0.72 | LMNA (0.32) | — | |
| Potassium Ion SCHEMBL10480425 | 0.72 | — | — | |
| SCHEMBL21422806 | 0.70 | NR1I2 (0.32) | NR1I2RORARORCRORBNR1H4 | |
| SCHEMBL6825672 | 0.70 | CA1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283774-B1 | FLUORINATED ALKYLAMIDOSULFONATES, PREPARATION, USE AS FLAME-RETARDER AND POLYCARBONATE MOULDING MASSES CONTAINING THEM | BAYER AG (DE) | 1992-05-06 | — | — | EP | disclosed |
| EP-0283774-A2 | Fluorinated alkylamidosulfonates, preparation, use as flame-retarder and polycarbonate moulding masses containing them | BAYER AG (DE) | 1988-09-28 | — | — | EP | disclosed |