Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 2/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5245089 | 0.98 | SCN4A (0.38) | SCN4AKCNN4MEN1NPC1TSHR | |
| SCHEMBL6823351 | 0.82 | ESR2 (0.38) | ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2763256 | 0.78 | KCNN4 (0.39) | KCNN4SMN1; SMN2ALDH1A1ALOX15TAAR1 | |
| SCHEMBL9288039 | 0.74 | KCNN4 (0.42) | KCNN4MEN1KMT2AALDH1A1ALOX15 | |
| SCHEMBL13012364 | 0.73 | TSHR (0.43) | SCN4AMEN1NPC1TSHRRAB9A | |
| SCHEMBL29083527 | 0.72 | DRD2 (0.40) | SCN4AMEN1NPC1TSHRRAB9A | |
| Hydrochloric Acid SCHEMBL4174062 | 0.72 | SLC6A2 (0.38) | SCN4AKCNN4TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL17929073 | 0.72 | TSHR (0.39) | SCN4AMEN1NPC1TSHRRAB9A | |
| SCHEMBL9707204 | 0.72 | MAPK1 (0.52) | SCN4AMEN1NPC1TSHRRAB9A | |
| SCHEMBL9289408 | 0.72 | KCNN4 (0.41) | KCNN4SMN1; SMN2ALDH1A1ALOX15CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379492-A1 | INHIBITOR OF MONOAMINE UPTAKE | ELI LILLY AND COMPANY (US) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002070457-A1 | INHIBITOR OF MONOAMINE UPTAKE | ELI LILLY AND COMPANY (US) | 2002-09-12 | — | — | WO | disclosed |