Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 16/20 | 0.58 |
| ▸ | PLAU | P00749 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | TACR3 | P29371 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824610 | 0.83 | KDM4E (0.78) | TRPV1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL4808201 | 0.81 | ALDH1A1 (0.72) | TRPV1PLAUKDM4EMEN1ALDH1A1 | |
| SCHEMBL30125017 | 0.81 | TRPV1 (0.70) | TRPV1PLAUKDM4EMEN1KMT2A | |
| SCHEMBL1413214 | 0.81 | TRPV1 (0.70) | TRPV1PLAUKDM4EMEN1KMT2A | |
| SCHEMBL8017317 | 0.79 | TRPV1 (0.61) | TRPV1PLAUKDM4EMEN1ALDH1A1 | |
| SCHEMBL6825453 | 0.75 | TRPV1 (0.84) | TRPV1KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL3034797 | 0.74 | MIF (0.60) | KDM4EMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL31680675 | 0.74 | TRPV1 (0.64) | TRPV1KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL14974717 | 0.74 | ALDH1A1 (0.63) | TRPV1PLAUKDM4EMEN1ALDH1A1 | |
| SCHEMBL487254 | 0.74 | TRPV1 (0.64) | TRPV1KDM4EMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089877-A1 | NEW HYDROXYNAPHTHYL AMIDES | ASTRAZENECA AB (SE) | 2004-10-21 | — | — | WO | claimed |
| WO-2004089877-A1 | NEW HYDROXYNAPHTHYL AMIDES | ASTRAZENECA AB (SE) | 2004-10-21 | — | — | WO | disclosed |