SCHEMBL4808201

SCHEMBL4808201

CCOC(=O)Nc1cccc2ccc(O)cc12

nearest known ligand 0.72

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.72
HPGD P15428 1/20 0.72
TRPV1 Q8NER1 15/20 0.64
KDM4E B2RXH2 1/20 0.54
MEN1 O00255 1/20 0.54
MAPT P10636 1/20 0.54
RAB9A P51151 1/20 0.54
KMT2A Q03164 1/20 0.54
PLAU P00749 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8017317 0.89 TRPV1 (0.61) ALDH1A1HPGDTRPV1KDM4EMEN1
SCHEMBL11766437 0.87 ALDH1A1 (0.77) ALDH1A1HPGDTRPV1KDM4EMEN1
SCHEMBL1413214 0.85 TRPV1 (0.70) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL30125017 0.85 TRPV1 (0.70) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL283472 0.84 ALDH1A1 (1.00) ALDH1A1HPGDKDM4EMAPTRAB9A
SCHEMBL11656966 0.83 ALDH1A1 (0.76) ALDH1A1HPGDTRPV1KDM4EMEN1
SCHEMBL6825893 0.81 TRPV1 (0.58) ALDH1A1TRPV1KDM4EMEN1RAB9A
SCHEMBL8021152 0.81 TRPV1 (0.61) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL31680675 0.81 TRPV1 (0.64) TRPV1KDM4EMEN1MAPTRAB9A
SCHEMBL487254 0.81 TRPV1 (0.64) TRPV1KDM4EMEN1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-57053565-A None JP disclosed
US-7413837-B2 Charge control agent and toner for electrostatic image development containing the same ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 2008-08-19 US disclosed
US-20050208409-A1 Charge control agent and toner for electrostatic image development containing the same ORIENT CHEMICAL INDUSTRIES LTD. (JP) 2005-09-22 US disclosed
CN-1181050-C Novel substituted dimeric compounds, its preparing process and medicinal compsns. containing same ɪά��ʵ���� 2004-12-22 CN disclosed
EP-0648816-B1 Dyeing of leather with dyestuff mixtures CIBA SC HOLDING AG (CH) 2000-01-26 EP disclosed
EP-0648816-A1 Dyeing of leather with dyestuff mixtures CIBA-GEIGY AG (CH) 1995-04-19 EP disclosed
US-5204453-A Process for the preparation of 1:2 metal complex azo compounds by carrying out diazotization and coupling in the presence of a metal donor CIBA-GEIGY CORPORATION (US) 1993-04-20 US disclosed
US-5002586-A Dyeing and printing of leather SANDOZ LTD. (CH) 1991-03-26 US disclosed
US-5001227-A Fibre-reactive 1:1 chromium complex azo or azomethine dyes having a bidentate chelating group and a monofunctional neutral ligand CIBA-GEIGY CORPORATION (US) 1991-03-19 US disclosed
US-4990598-A Colorfastness CIBA-GEIGY CORPORATION, A CORP. OF NEW YORK 1991-02-05 US disclosed
US-4219473-A Substituted unsymmetrical azo, azomethine 1:2 chromium complexes CIBA-GEIGY CORPORATION (US) 1980-08-26 US disclosed
US-4215042-A PRINTING AND DYEING OF POLYAMIDES; COLORFASTNESS CIBA-GEIGY CORPORATION (US) 1980-07-29 US disclosed
US-4116952-A POLYAMIDES CIBA-GEIGY CORPORATION (US) 1978-09-26 US disclosed
US-RE29585-E DYEING WOOL CIBA-GEIGY CORPORATION (US) 1978-03-21 US disclosed
US-4053462-A UNSYMMETRICAL PHENYL AZO NAPHTHYL CHROMIUM COMPLEX DYES CIBA-GEIGY CORPORATION (US) 1977-10-11 US disclosed
US-4033942-A Chromium complex dye, including azo and azo methine dye compounds CIBA-GEIGY AG (CH) 1977-07-05 US disclosed
US-4005065-A GOOD FASTNESS TO LIGHT, PERSPIRATION, FULLING, DECATIZING AND CARBONIZING CIBA-GEIGY CORPORATION (US) 1977-01-25 US disclosed
US-3978037-A POLYAMIDES CIBA-GEIGY CORPORATION (US) 1976-08-31 US disclosed
US-3971738-A Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component CIBA-GEIGY AG (CH) 1976-07-27 US disclosed
US-3933785-A Azo compounds CIBA-GEIGY AG (CH) 1976-01-20 US disclosed