Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 9/20 | 0.58 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.58 |
| ▸ | TUBB | P07437 | 1/20 | 0.58 |
| ▸ | YES1 | P07947 | 1/20 | 0.58 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.58 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.58 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.58 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.58 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.58 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.58 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.58 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.58 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.58 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.58 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.58 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6825975 | 0.78 | MAOB (0.56) | CYP19A1MAOBKDM4EAR | |
| SCHEMBL9749344 | 0.76 | CYP19A1 (0.63) | CYP19A1TUBB4ATUBBYES1TUBA3C | |
| SCHEMBL6828122 | 0.76 | PBRM1 (0.61) | CYP19A1MAOAMAOBAR | |
| Liquirtigenin SCHEMBL1071066 | 0.74 | CYP19A1 (1.00) | CYP19A1TUBB4ATUBBYES1TUBA3C | |
| Liquirtigenin SCHEMBL26970367 | 0.74 | CYP19A1 (1.00) | CYP19A1TUBB4ATUBBYES1TUBA3C | |
| SCHEMBL17960537 | 0.74 | CYP19A1 (0.62) | CYP19A1TUBB4ATUBBYES1TUBA3C | |
| Liquirtigenin SCHEMBL74552 | 0.74 | CYP19A1 (1.00) | CYP19A1TUBB4ATUBBYES1TUBA3C | |
| Liquirtigenin SCHEMBL29552383 | 0.74 | CYP19A1 (1.00) | CYP19A1TUBB4ATUBBYES1TUBA3C | |
| Liquirtigenin SCHEMBL30352791 | 0.74 | CYP19A1 (1.00) | CYP19A1TUBB4ATUBBYES1TUBA3C | |
| SCHEMBL6827986 | 0.73 | RAB9A (0.51) | CYP19A1MAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004113317-A1 | NOVEL ANTIMICROBIAL CHROMAN-4-ONES | ERNST-MORITZ-ARNDT- UNIVERSITÄT (DE) | 2004-12-29 | — | — | WO | claimed |
| WO-2004113317-A1 | NOVEL ANTIMICROBIAL CHROMAN-4-ONES | ERNST-MORITZ-ARNDT- UNIVERSITÄT (DE) | 2004-12-29 | — | — | WO | disclosed |