Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6922023 | 0.84 | ALDH1A1 (0.45) | KMT2AMAPTKDM4EHSD17B10HTT | |
| SCHEMBL6922029 | 0.84 | ALDH1A1 (0.45) | KMT2AMAPTKDM4EHSD17B10HTT | |
| SCHEMBL6919316 | 0.77 | ALDH1A1 (0.53) | KMT2AMAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8276659 | 0.72 | KDM4E (0.61) | KMT2AMAPTKDM4EHSD17B10HTT | |
| SCHEMBL8236497 | 0.72 | KDM4E (0.61) | KMT2AMAPTKDM4EHSD17B10HTT | |
| SCHEMBL6826235 | 0.69 | ALDH1A1 (0.40) | KMT2AMAPTKDM4EHSD17B10HTT | |
| SCHEMBL6826234 | 0.69 | ALDH1A1 (0.40) | KMT2AMAPTKDM4EHSD17B10HTT | |
| SCHEMBL28357458 | 0.68 | ALDH1A1 (0.48) | KMT2AMAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL7597398 | 0.68 | ALDH1A1 (0.65) | KMT2AKDM4EHTTALDH1A1LMNA | |
| SCHEMBL38652677 | 0.64 | KMT2A (0.45) | KMT2AMAPTKDM4EHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004111052-A1 | PYRROLOPYRIMIDINE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE (MDR) | XENOVA LIMITED (GB) | 2004-12-23 | — | — | WO | disclosed |