Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 13/20 | 0.74 |
| ▸ | RAB9A | P51151 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5694477 | 0.94 | TRPV1 (0.77) | TRPV1RAB9ANPC1CYP1A2CYP3A4 | |
| SCHEMBL11726742 | 0.85 | TRPV1 (0.76) | TRPV1RAB9ANPC1CYP1A2CYP3A4 | |
| SCHEMBL11422447 | 0.85 | TRPV1 (1.00) | TRPV1RAB9ANPC1CYP1A2CYP3A4 | |
| SCHEMBL2747077 | 0.83 | NPC1 (0.71) | TRPV1RAB9ANPC1CYP1A2CYP3A4 | |
| SCHEMBL15782671 | 0.83 | TRPV1 (0.72) | TRPV1RAB9ANPC1CYP1A2CYP3A4 | |
| SCHEMBL7539037 | 0.81 | NPC1 (0.78) | TRPV1RAB9ANPC1CYP1A2CYP3A4 | |
| SCHEMBL6825915 | 0.81 | TRPV1 (0.69) | TRPV1RAB9ANPC1CYP1A2CYP3A4 | |
| SCHEMBL12172779 | 0.80 | GFER (0.69) | TRPV1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL2676769 | 0.79 | TRPV1 (0.70) | TRPV1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL4642544 | 0.79 | NPC1 (1.00) | RAB9ANPC1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089877-A1 | NEW HYDROXYNAPHTHYL AMIDES | ASTRAZENECA AB (SE) | 2004-10-21 | — | — | WO | claimed |
| WO-2004089877-A1 | NEW HYDROXYNAPHTHYL AMIDES | ASTRAZENECA AB (SE) | 2004-10-21 | — | — | WO | disclosed |