Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12443811 | 0.83 | MEN1 (0.48) | KMT2AMEN1RAB9ANPC1ATM | |
| SCHEMBL20390512 | 0.80 | MEN1 (0.56) | KMT2AMEN1RAB9ANPC1ATM | |
| SCHEMBL30128655 | 0.80 | MAPT (0.56) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL13662705 | 0.80 | MEN1 (0.56) | KMT2AMEN1RAB9ANPC1CYP1A2 | |
| SCHEMBL30911587 | 0.79 | CYP2A6 (0.40) | KMT2AMEN1RAB9ANPC1ATM | |
| SCHEMBL3794168 | 0.79 | TRPV3 (0.48) | SCN9AKCNH2 | |
| SCHEMBL1828161 | 0.79 | ADORA2A (0.53) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL1018167 | 0.79 | NPC1 (0.47) | KMT2AMEN1NPC1ATMMAPT | |
| SCHEMBL27754726 | 0.78 | HSP90AA1 (0.42) | KMT2AMEN1SCN9AKCNH2SCN5A | |
| Hydrochloric Acid SCHEMBL11514438 | 0.78 | NPC1 (0.46) | KMT2AMEN1NPC1ATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046118-A2 | 2-4-(DI-PHENYL-AMINO)-PYRIMIDINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS | BAYER PHARMACEUTICALS CORPORATION (US) | 2004-06-03 | — | — | WO | disclosed |