Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | PRKACA | P17612 | 1/20 | 0.48 |
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30681806 | 0.84 | LTA4H (0.49) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL12443811 | 0.83 | MEN1 (0.48) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL1018167 | 0.83 | NPC1 (0.47) | ADORA2BPOLBHSP90AA1MEN1KMT2A | |
| SCHEMBL27754726 | 0.81 | HSP90AA1 (0.42) | HSP90AA1MEN1KMT2AKDM4EGABRA1 | |
| Hydrochloric Acid SCHEMBL11514438 | 0.81 | NPC1 (0.46) | ADORA2BPOLBHSP90AA1MEN1KMT2A | |
| SCHEMBL2885661 | 0.80 | MEN1 (0.51) | POLBASIC3MEN1KMT2ANPC1 | |
| SCHEMBL29933915 | 0.80 | CYP2A6 (0.62) | POLBHSP90AA1MEN1KMT2AHTT | |
| SCHEMBL4631413 | 0.80 | CYP2A6 (0.62) | POLBHSP90AA1MEN1KMT2AHTT | |
| SCHEMBL30681803 | 0.80 | SCN9A (0.46) | ADORA2AADORA1MEN1KMT2AMAPT | |
| SCHEMBL1921676 | 0.79 | NOS2 (0.44) | HSP90AA1KDM4EL3MBTL1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1701122-A | Crystal structure of PIM-1 kinase | PLEXXIKON INC (US) | 2005-11-23 | — | — | CN | claimed |
| CN-1479630-A | Methods of inducing cancer cell death and tumor regression | Q | 2004-03-03 | — | — | CN | claimed |
| US-20250145642-A1 | BICYCLIC HETEROARENES AND METHODS OF THEIR USE | Kineta, Inc. | 2025-05-08 | — | — | US | disclosed |
| US-20250127716-A1 | INHALED IMATINIB FOR TREATMENT OF PULMONARY HYPERTENSION | JUSTUS-LIEBIG-UNIVERSITAET GIESSEN (DE) | 2025-04-24 | — | — | US | disclosed |
| EP-4507745-A1 | EMULSION FORMULATIONS OF POORLY WATER-SOLUBLE COMPOUNDS | Menning, Mark Michael (US) | 2025-02-19 | — | — | EP | disclosed |
| US-20240409609-A1 | REVERSIBLE LYSINE COVALENT MODIFIERS OF EGFR AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. | 2024-12-12 | — | — | US | disclosed |
| EP-4472609-A1 | INHALED IMATINIB FOR TREATMENT OF PULMONARY HYPERTENSION | Justus-Liebig-Universität Gießen (DE) | 2024-12-11 | — | — | EP | disclosed |
| CN-118946360-A | Bicyclic heteroarenes and methods of use thereof | 奇尼塔公司 | 2024-11-12 | — | — | CN | disclosed |
| EP-4444317-A2 | BICYCLIC HETEROARENES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| US-20230330019-A1 | EMULSION FORMULATIONS OF POORLY WATER-SOLUBLE COMPOUNDS | MENNING MARK MICHAEL (US) | 2023-10-19 | — | — | US | disclosed |
| WO-2023201042-A1 | EMULSION FORMULATIONS OF POORLY WATER-SOLUBLE COMPOUNDS | MENNING MARK MICHAEL (US) | 2023-10-19 | — | — | WO | disclosed |
| EP-0671881-A4 | INSECTICIDAL 5-SUBSTITUTED-2,4-DIAMINOPYRIMIDINE DERIVATIVES. | FMC CORP (US) | 1996-03-27 | — | — | EP | disclosed |
| EP-0671881-A1 | INSECTICIDAL 5-SUBSTITUTED-2,4-DIAMINOPYRIMIDINE DERIVATIVES | FMC CORPORATION (US) | 1995-09-20 | — | — | EP | disclosed |
| EP-0650481-A1 | PYRIMIDINE COMPOUNDS USED IN THE THERAPY | BTG INTERNATIONAL LIMITED (GB) | 1995-05-03 | — | — | EP | disclosed |
| CN-1096156-A | 5-replaces-2,4-diaminopyrimidine derivatives insecticide | FMC CORP (US) | 1994-12-14 | — | — | CN | disclosed |
| WO-1994012032-A1 | INSECTICIDAL 5-SUBSTITUTED-2,4-DIAMINOPYRIMIDINE DERIVATIVES | FMC CORPORATION (US) | 1994-06-09 | — | — | WO | disclosed |
| WO-1994002469-A1 | PYRIMIDINE COMPOUNDS USED IN THE THERAPY | BRITISH TECHNOLOGY GROUP LTD. (GB) | 1994-02-03 | — | — | WO | disclosed |
| US-4323681-A | IMMUNOMODULATOR AGENTS HAVING STIMULANT OR SUPPRESSANT EFFECT FOR TREATMENT OF AUTOIMMUNE DISORDERS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-04-06 | — | — | US | disclosed |
| EP-0019811-A1 | Pyrimidine compounds, process for their preparation, pharmaceutical compositions containing them and their therapeutical use | CIBA-GEIGY AG (CH) | 1980-12-10 | — | — | EP | disclosed |
| US-4109092-A | FROM PYRIDINYL-CARBOXAMIDINE AND ALPHA-CHLOROACRYLONITRILE | STERLING DRUG INC. (US) | 1978-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230330019-A1 | EMULSION FORMULATIONS OF POORLY WATER-SOLUBLE COMPOUNDS | CUTA, SUCLG1, TYR | ADORA2A 4799/4885ADORA1 4618/4885ADORA3 4762/4885 |
| US-20240409609-A1 | REVERSIBLE LYSINE COVALENT MODIFIERS OF EGFR AND USES THEREOF | EGFR, ERBB2, ERBB3 | ADORA2A 3600/4885ADORA1 4528/4885ADORA3 3957/4885 |
| US-20250145642-A1 | BICYCLIC HETEROARENES AND METHODS OF THEIR USE | TARDBP, TDP2, PSEN2 | ADORA2A 963/4885ADORA1 2880/4885ADORA3 2184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.