Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829140 | 0.90 | HRH3 (0.55) | SLC2A1LMNAKDM4ETSHRHPGD | |
| SCHEMBL6831430 | 0.89 | SLC2A1 (0.55) | SLC2A1KDM4ETSHRHPGDHSD17B10 | |
| SCHEMBL6925801 | 0.89 | KDM4E (0.48) | SLC2A1LMNAKDM4ETSHRHPGD | |
| SCHEMBL6829881 | 0.83 | SLC2A1 (0.56) | SLC2A1LMNATSHRHPGDALDH1A1 | |
| SCHEMBL6830116 | 0.83 | KDM4E (0.51) | SLC2A1LMNAKDM4ETSHRHPGD | |
| SCHEMBL6826365 | 0.82 | SLC2A1 (0.57) | SLC2A1LMNAALDH1A1HRH3HDAC3 | |
| SCHEMBL6826410 | 0.81 | SLC2A1 (0.55) | SLC2A1LMNATSHRHPGDALDH1A1 | |
| SCHEMBL6826496 | 0.80 | SLC2A1 (0.54) | SLC2A1LMNATSHRHPGDALDH1A1 | |
| SCHEMBL6826756 | 0.80 | DRD2 (0.54) | SLC2A1LMNAKDM4ETSHRHPGD | |
| SCHEMBL6826373 | 0.79 | HRH3 (0.58) | SLC2A1KDM4ETSHRHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108671-A1 | SUBSTITUTED INDOLES WITH SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-12-16 | — | — | WO | claimed |
| WO-2004108671-A1 | SUBSTITUTED INDOLES WITH SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-12-16 | — | — | WO | disclosed |