Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826421 | 0.90 | SLC2A1 (0.55) | HRH3TSHRNOD2NOD1KDM4E | |
| SCHEMBL6826373 | 0.89 | HRH3 (0.58) | HRH3TSHRNOD2NOD1KDM4E | |
| SCHEMBL6925801 | 0.89 | KDM4E (0.48) | HRH3TSHRKDM4ELMNASLC2A1 | |
| SCHEMBL6921864 | 0.84 | HRH3 (0.51) | HRH3NOD2NOD1LMNASLC2A1 | |
| SCHEMBL6830116 | 0.83 | KDM4E (0.51) | HRH3TSHRKDM4ELMNASLC2A1 | |
| SCHEMBL6829301 | 0.82 | NOD2 (0.60) | HRH3NOD2NOD1LMNASLC2A1 | |
| SCHEMBL6829377 | 0.82 | HRH3 (0.53) | HRH3TSHRNOD2NOD1LMNA | |
| SCHEMBL6829439 | 0.81 | HRH3 (0.49) | HRH3NOD2NOD1LMNASLC2A1 | |
| SCHEMBL6829317 | 0.80 | HTR6 (0.49) | HRH3TSHRKDM4ELMNASLC2A1 | |
| SCHEMBL6831430 | 0.79 | SLC2A1 (0.55) | HRH3TSHRKDM4ESLC2A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108671-A1 | SUBSTITUTED INDOLES WITH SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-12-16 | — | — | WO | claimed |
| WO-2004108671-A1 | SUBSTITUTED INDOLES WITH SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-12-16 | — | — | WO | disclosed |