Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | THRB | P10828 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | PLG | P00747 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.62 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28821576 | 0.97 | LMNA (0.65) | LMNAKMT2ATHRBMEN1ALDH1A1 | |
| SCHEMBL5193962 | 0.97 | LMNA (0.65) | LMNAKMT2ATHRBMEN1ALDH1A1 | |
| SCHEMBL152548 | 0.97 | LMNA (0.65) | LMNAKMT2ATHRBMEN1ALDH1A1 | |
| SCHEMBL10933283 | 0.94 | NFKB1 (0.57) | LMNAKMT2ATHRBMEN1ALDH1A1 | |
| SCHEMBL5961191 | 0.91 | LMNA (0.57) | LMNAKMT2ATHRBMEN1ALDH1A1 | |
| SCHEMBL2400675 | 0.91 | LMNA (0.57) | LMNAKMT2ATHRBMEN1ALDH1A1 | |
| SCHEMBL10932293 | 0.91 | LMNA (0.57) | LMNAKMT2ATHRBMEN1ALDH1A1 | |
| SCHEMBL11806372 | 0.89 | KMT2A (0.56) | LMNAKMT2ATHRBMEN1ALDH1A1 | |
| SCHEMBL7166225 | 0.89 | KMT2A (0.56) | LMNAKMT2ATHRBMEN1ALDH1A1 | |
| SCHEMBL6738249 | 0.89 | KMT2A (0.56) | LMNAKMT2ATHRBMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392755-A1 | LIPID-POLYMER-CONJUGATES COMPOSITIONS | YAMANOUCHI EUROPE B.V. (NL) | 2004-03-03 | — | — | EP | claimed |
| WO-2002098952-A1 | LIPID-POLYMER-CONJUGATES COMPOSITIONS | YAMANOUCHI EUROPE B.V. (NL) | 2002-12-12 | — | — | WO | claimed |
| WO-2012095516-A1 | HUMAN ANTIBODIES CROSS-REACTING WITH A BACTERIAL AND A SELF ANTIGEN FROM ATHEROSCLEROTIC PLAQUES | BRACCO IMAGING SPA (IT) | 2012-07-19 | — | — | WO | disclosed |