Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 6/20 | 0.52 |
| ▸ | MAOB | P27338 | 6/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 7-Methoxychromone SCHEMBL1854902 | 0.83 | KDM4E (1.00) | KDM4EFTOMAOAMAOBCYP19A1 | |
| 7-Methoxychromone SCHEMBL31260290 | 0.83 | KDM4E (1.00) | KDM4EFTOMAOAMAOBCYP19A1 | |
| SCHEMBL26661256 | 0.79 | KDM4E (0.69) | KDM4EFTOMAOAMAOBCA12 | |
| 7-Methoxychromone SCHEMBL28430247 | 0.78 | KDM4E (0.88) | KDM4EFTOMAOAMAOBCA12 | |
| SCHEMBL741245 | 0.78 | KDM4E (0.67) | KDM4EFTOMAOAMAOBCA12 | |
| SCHEMBL29019091 | 0.76 | KDM4E (0.65) | KDM4EFTOMAOAMAOBCA12 | |
| SCHEMBL26661270 | 0.76 | KDM4E (0.65) | KDM4EMAOAMAOBCA12CA1 | |
| SCHEMBL17708884 | 0.75 | KDM4E (0.64) | KDM4EFTOMAOAMAOBCA12 | |
| 7-Methoxychromone SCHEMBL28423141 | 0.75 | KDM4E (0.82) | KDM4EFTOMAOAMAOBCA12 | |
| SCHEMBL28776653 | 0.74 | KDM4E (0.62) | KDM4EFTOMAOAMAOBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004113317-A1 | NOVEL ANTIMICROBIAL CHROMAN-4-ONES | ERNST-MORITZ-ARNDT- UNIVERSITÄT (DE) | 2004-12-29 | — | — | WO | disclosed |