Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 1.00 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 5/20 | 0.55 |
| ▸ | MAOA | P21397 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | TNKS | O95271 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | STAT1 | P42224 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 7-Methoxychromone SCHEMBL31260290 | 1.00 | KDM4E (1.00) | KDM4EFTOMAOBMAOAALDH1A1 | |
| 7-Methoxychromone SCHEMBL28430247 | 0.94 | KDM4E (0.88) | KDM4EFTOMAOBMAOAALDH1A1 | |
| 7-Methoxychromone SCHEMBL28423141 | 0.91 | KDM4E (0.82) | KDM4EFTOMAOBMAOAALDH1A1 | |
| 7-Methoxychromone SCHEMBL28428762 | 0.89 | KDM4E (0.80) | KDM4EFTOMAOBMAOAALDH1A1 | |
| 7-Methoxychromone SCHEMBL28428753 | 0.89 | KDM4E (0.80) | KDM4EFTOMAOBMAOAALDH1A1 | |
| Pentadecane SCHEMBL28423089 | 0.89 | KDM4E (0.80) | KDM4EFTOMAOBMAOAALDH1A1 | |
| SCHEMBL28124918 | 0.87 | KDM4E (0.77) | KDM4EFTOMAOBMAOAALDH1A1 | |
| SCHEMBL8871485 | 0.86 | KDM4E (0.75) | KDM4EMAOBMAOAALDH1A1MAPT | |
| SCHEMBL6826684 | 0.83 | KDM4E (0.71) | KDM4EFTOMAOBMAOACYP19A1 | |
| SCHEMBL26661256 | 0.81 | KDM4E (0.69) | KDM4EFTOMAOBMAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113372318-A | Preparation method and device of 7-methoxy-4' -methyl formate flavanone | 贵州中医药大学 | 2021-09-10 | — | — | CN | claimed |
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | claimed |
| JP-9188608-A | — | — | None | — | — | JP | disclosed |
| EP-4474446-B1 | ELECTROCHROMIC COMPOUNDS, COMPOSITIONS AND DEVICES COMPRISING THE SAME | ESSILOR INT (FR) | 2025-12-17 | — | — | EP | disclosed |
| WO-2025036382-A1 | SULFONAMIDE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海复宏汉霖生物医药有限公司 | 2025-02-20 | — | — | WO | disclosed |
| CN-116120313-B | Pyridoimidazole nitrogen fused ring compound and preparation method and application thereof | 遵义医科大学 | 2025-02-11 | — | — | CN | disclosed |
| WO-2024251948-A1 | ELECTROCHROMIC COMPOUNDS, COMPOSITIONS AND DEVICES COMPRISING THE SAME | ESSILOR INTERNATIONAL (FR) | 2024-12-12 | — | — | WO | disclosed |
| EP-4474446-A1 | ELECTROCHROMIC COMPOUNDS, COMPOSITIONS AND DEVICES COMPRISING THE SAME | Essilor International (FR) | 2024-12-11 | — | — | EP | disclosed |
| CN-113999223-B | Thiazole-containing flavonoid derivative, preparation method and application thereof | 扬州大学 | 2023-12-19 | — | — | CN | disclosed |
| CN-116120313-A | Pyridoimidazole nitrogen fused ring compound and preparation method and application thereof | 遵义医科大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-112759580-B | Preparation method of chroman-4-one and derivatives thereof | 河南大学 | 2022-05-17 | — | — | CN | disclosed |
| EP-1732913-A1 | CHROMONE COMPLEXES | MERCK PATENT GmbH (DE) | 2006-12-20 | — | — | EP | disclosed |
| WO-2006128562-A1 | USE OF CHROMONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2006-12-07 | — | — | WO | disclosed |
| WO-2006094601-A1 | CHROMEN-4-ONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2006-09-14 | — | — | WO | disclosed |
| EP-1656364-A1 | CHROMEN-4-ONE DERIVATIVES | MERCK PATENT GmbH (DE) | 2006-05-17 | — | — | EP | disclosed |
| WO-2005097772-A1 | CHROMONE COMPLEXES | MERCK PATENT GMBH (DE) | 2005-10-20 | — | — | WO | disclosed |
| WO-2005019197-A1 | CHROMEN-4-ONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2005-03-03 | — | — | WO | disclosed |
| US-20050043398-A1 | Use of chromen-4-one derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2005-02-24 | — | — | US | disclosed |
| EP-1508327-A1 | Use of chromen-4-one derivatives for the care of skin and hair | MERCK PATENT GmbH (DE) | 2005-02-23 | — | — | EP | disclosed |
| JP-H09188608-A | GREY HAIR PREVENTIVE AGENT | KAO CORP | 1997-07-22 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043398-A1 | Use of chromen-4-one derivatives | CYP8B1, CYP7B1, CYP2R1 | KDM4E 1606/4885FTO 321/4885MAOB 796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.