Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | CALML3 | P27482 | 1/20 | 0.43 |
| ▸ | SDHA | P31040 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828025 | 0.92 | MAOA (0.53) | MAOAMAOBALDH1A1NPC1HPGD | |
| SCHEMBL3396494 | 0.88 | MAOB (0.54) | MAOAMAOBALDH1A1LMNAPTGS1 | |
| SCHEMBL6826876 | 0.83 | SLC2A1 (0.47) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL6826900 | 0.80 | MAOB (0.44) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL3390768 | 0.80 | MAOB (0.55) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL3396487 | 0.79 | MAOB (0.55) | MAOAMAOBALDH1A1LMNAPTGS1 | |
| SCHEMBL3394631 | 0.78 | F10 (0.54) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL3434968 | 0.78 | ALDH1A1 (0.47) | MAOAMAOBALDH1A1NPC1HPGD | |
| SCHEMBL6397262 | 0.77 | MAOA (0.53) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL6397255 | 0.77 | MAOA (0.53) | MAOAMAOBLMNAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004113329-A1 | OXAZOLE DERIVATIVES AS ANTIBACTERIAL AGENTS | ORCHID CHEMICALS AND PHARMACEUTICALS LTD. (IN) | 2004-12-29 | — | — | WO | claimed |
| WO-2004113329-A1 | OXAZOLE DERIVATIVES AS ANTIBACTERIAL AGENTS | ORCHID CHEMICALS AND PHARMACEUTICALS LTD. (IN) | 2004-12-29 | — | — | WO | disclosed |