Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CFD | P00746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4370866 | 0.88 | CA12 (0.42) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL5283277 | 0.83 | KDM4E (0.43) | KDM4ENFE2L2EGFRCYP4F2CYP4A11 | |
| SCHEMBL24736066 | 0.82 | KDM4E (0.41) | KDM4ESLC7A5NFE2L2EGFRCYP4F2 | |
| SCHEMBL8153586 | 0.81 | GABRA1 (0.41) | KDM4EPPARA | |
| SCHEMBL31455672 | 0.81 | KDM4E (0.40) | KDM4ESLC7A5NFE2L2EGFRCYP4F2 | |
| SCHEMBL3875526 | 0.78 | BID (0.53) | KDM4EDUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL28023544 | 0.74 | TSHR (0.43) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL11590731 | 0.73 | CA12 (0.67) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL29907828 | 0.72 | SMN1; SMN2 (0.47) | KDM4EEGFRSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL23270686 | 0.72 | SMN1; SMN2 (0.47) | KDM4EEGFRSMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406867-A2 | THIOLALKYL BENZOIC ACID DERIVATIVES | GUILFORD PHARMACEUTICALS INC. (US) | 2004-04-14 | — | — | EP | disclosed |
| WO-2002096866-A2 | THIOLALKYL BENZOIC ACID DERIVATIVES | GUILFORD PHARMACEUTICALS INC. (US) | 2002-12-05 | — | — | WO | disclosed |