Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5283277 | 0.84 | KDM4E (0.43) | KDM4ESMN1; SMN2EGFRCYP4F2CYP4A11 | |
| SCHEMBL24736066 | 0.83 | KDM4E (0.41) | KDM4ESMN1; SMN2EGFRCYP4F2CYP4A11 | |
| SCHEMBL4370866 | 0.81 | CA12 (0.42) | KDM4ESMN1; SMN2EGFRCYP4F2CYP4A11 | |
| SCHEMBL6826872 | 0.81 | KDM4E (0.39) | KDM4ESMN1; SMN2EGFRCYP4F2CYP4A11 | |
| SCHEMBL506923 | 0.79 | SMN1; SMN2 (0.46) | KDM4ESMN1; SMN2CYP4F2CYP4A11HTT | |
| SCHEMBL29907828 | 0.79 | SMN1; SMN2 (0.47) | KDM4ESMN1; SMN2EGFRL3MBTL1TSHR | |
| SCHEMBL23270686 | 0.79 | SMN1; SMN2 (0.47) | KDM4ESMN1; SMN2EGFRL3MBTL1TSHR | |
| SCHEMBL2972991 | 0.78 | MEP1B (0.48) | KDM4ESMN1; SMN2EGFRCYP4F2CYP4A11 | |
| SCHEMBL16950364 | 0.77 | GABRA1 (0.40) | MEN1KMT2AALDH1A1 | |
| SCHEMBL18261999 | 0.76 | KDM4E (0.43) | KDM4ESMN1; SMN2EGFRCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059562-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |