Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6310213 | 1.00 | SLC10A2 (0.57) | SLC10A2 | |
| SCHEMBL6222848 | 1.00 | SLC10A2 (0.57) | SLC10A2 | |
| SCHEMBL6310208 | 1.00 | SLC10A2 (0.57) | SLC10A2 | |
| SCHEMBL6428958 | 1.00 | SLC10A2 (0.57) | SLC10A2 | |
| SCHEMBL6827161 | 0.73 | SLC10A2 (1.00) | SLC10A2 | |
| SCHEMBL6829423 | 0.73 | SLC10A2 (1.00) | SLC10A2 | |
| SCHEMBL6827058 | 0.73 | SLC10A2 (1.00) | SLC10A2 | |
| SCHEMBL6220086 | 0.73 | SLC10A2 (1.00) | SLC10A2 | |
| SCHEMBL6921164 | 0.73 | SLC10A2 (1.00) | SLC10A2 | |
| SCHEMBL6200982 | 0.73 | SLC10A2 (0.47) | SLC10A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6740663-B2 | ANTIHYPERLIPIDEMIC AGENTS | G.D. SEARLE, LLC | 2004-05-25 | — | — | US | disclosed |
| US-6420417-B1 | TREATMENT OF HYPERLIPIDEMIC CONDITIONS SUCH AS THOSE ASSOCIATED WITH ATHEROSCLEROSIS OR HYPERCHOLESTEROLEMIA IN MAMMALS | G. D. SEARLE & CO. | 2002-07-16 | — | — | US | disclosed |
| US-6268392-B1 | Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors | G. D. SEARLE & CO. | 2001-07-31 | — | — | US | disclosed |
| US-6262277-B1 | IN MEDICINE FOR PROPHYLAXIS AND THERAPY OF HYPERLIPIDEMIC CONDITIONS SUCH AS THOSE ASSOCIATED WITH ATHEROSCLEROSIS OR HYPERCHOLESTEROLEMIA, IN MAMMALS | G.D. SEARLE AND COMPANY | 2001-07-17 | — | — | US | disclosed |