SCHEMBL6829423

SCHEMBL6829423

CCCC[C@]1(CC)CS(=O)(=O)c2ccccc2[C@@H](c2ccccc2)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC10A2 Q12908 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6827058 1.00 SLC10A2 (1.00) SLC10A2
SCHEMBL6921164 1.00 SLC10A2 (1.00) SLC10A2
SCHEMBL6827161 1.00 SLC10A2 (1.00) SLC10A2
SCHEMBL6220086 1.00 SLC10A2 (1.00) SLC10A2
SCHEMBL8457213 0.91 SLC10A2 (0.84) SLC10A2
SCHEMBL6222198 0.91 SLC10A2 (0.84) SLC10A2
SCHEMBL6224734 0.88 SLC10A2 (1.00) SLC10A2
SCHEMBL6224730 0.88 SLC10A2 (1.00) SLC10A2
SCHEMBL6222284 0.87 SLC10A2 (1.00) SLC10A2
SCHEMBL1361679 0.87 SLC10A2 (0.78) SLC10A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10555950-B2 Bile acid recycling inhibitors for treatment of obesity and diabetes SATIOGEN PHARMACEUTICALS, INC. (US) 2020-02-11 US disclosed
US-10251880-B2 Bile acid recycling inhibitors and satiogens for treatment of diabetes, obesity, and inflammatory gastrointestinal conditions SATIOGEN PHARMACEUTICALS, INC. (US) 2019-04-09 US disclosed
US-20160220577-A1 BILE ACID RECYCLING INHIBITORS FOR TREATMENT OF OBESITY AND DIABETES SATIOGEN PHARMACEUTICALS, INC. 2016-08-04 US disclosed
US-20160220577-A1 BILE ACID RECYCLING INHIBITORS FOR TREATMENT OF OBESITY AND DIABETES SATIOGEN PHARMACEUTICALS, INC. 2016-08-04 US disclosed
US-20150087642-A1 BILE ACID RECYCLING INHIBITORS AND SATIOGENS FOR TREATMENT OF DIABETES, OBESITY, AND INFLAMMATORY GASTROINTESTINAL CONDITIONS SATIOGEN PHARMACEUTICALS, INC. 2015-03-26 US disclosed
US-20150087642-A1 BILE ACID RECYCLING INHIBITORS AND SATIOGENS FOR TREATMENT OF DIABETES, OBESITY, AND INFLAMMATORY GASTROINTESTINAL CONDITIONS SATIOGEN PHARMACEUTICALS, INC. 2015-03-26 US disclosed
US-6740663-B2 ANTIHYPERLIPIDEMIC AGENTS G.D. SEARLE, LLC 2004-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10251880-B2 Bile acid recycling inhibitors and satiogens for treatment of diabetes, obesity, and inflammatory gastrointestinal conditions SLC10A2, GPR119, GPBAR1 SLC10A2 1/4885
US-20150087642-A1 BILE ACID RECYCLING INHIBITORS AND SATIOGENS FOR TREATMENT OF DIABETES, OBESITY, AND INFLAMMATORY GASTROINTESTINAL CONDITIONS SLC10A2, GPR119, GPBAR1 SLC10A2 1/4885
US-10555950-B2 Bile acid recycling inhibitors for treatment of obesity and diabetes SLC10A1, SLC10A2, ABCB11 SLC10A2 2/4885
US-20160220577-A1 BILE ACID RECYCLING INHIBITORS FOR TREATMENT OF OBESITY AND DIABETES SLC10A1, SLC10A2, ABCB11 SLC10A2 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.