Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 9/20 | 0.59 |
| ▸ | EGFR | P00533 | 11/20 | 0.58 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6827053 | 0.87 | ERBB2 (0.64) | ERBB2EGFRERBB4 | |
| Hydrochloric Acid SCHEMBL6826891 | 0.81 | EGFR (0.62) | ERBB2EGFR | |
| SCHEMBL6826933 | 0.76 | ERBB2 (0.65) | ERBB2EGFRERBB4 | |
| SCHEMBL9910675 | 0.76 | EGFR (0.84) | ERBB2EGFRERBB4 | |
| Hydrochloric Acid SCHEMBL6826943 | 0.76 | ERBB2 (0.64) | ERBB2EGFRERBB4 | |
| SCHEMBL6827084 | 0.75 | EGFR (0.55) | EGFR | |
| Formic Acid SCHEMBL6826685 | 0.75 | EGFR (0.45) | ERBB2EGFRERBB4 | |
| SCHEMBL31061496 | 0.75 | ERBB2 (1.00) | ERBB2EGFRERBB4 | |
| SCHEMBL8554934 | 0.75 | ERBB2 (1.00) | ERBB2EGFRERBB4 | |
| SCHEMBL6483644 | 0.75 | ERBB2 (0.61) | ERBB2EGFRERBB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004112714-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-12-29 | — | — | WO | disclosed |