Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 10/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 6/20 | 0.36 |
| ▸ | ERBB4 | Q15303 | 4/20 | 0.36 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6825273 | 0.86 | EGFR (0.43) | EGFRERBB2ERBB4 | |
| SCHEMBL6236088 | 0.81 | PIP4K2A (0.40) | EGFRERBB2ERBB4PIP4K2ARIPK2 | |
| SCHEMBL6827006 | 0.75 | ERBB2 (0.59) | EGFRERBB2ERBB4 | |
| SCHEMBL6827084 | 0.72 | EGFR (0.55) | EGFRPIP4K2A | |
| SCHEMBL6239978 | 0.71 | EGFR (0.47) | EGFRERBB2ERBB4JAK3MKNK1 | |
| Hydrochloric Acid SCHEMBL6827053 | 0.70 | ERBB2 (0.64) | EGFRERBB2ERBB4JAK3 | |
| Hydrochloric Acid SCHEMBL6826891 | 0.68 | EGFR (0.62) | EGFRERBB2PIP4K2A | |
| Hydrochloric Acid SCHEMBL6826980 | 0.65 | EGFR (0.60) | EGFRERBB2PIP4K2A | |
| SCHEMBL6827146 | 0.64 | HTR6 (0.47) | — | |
| Hydrochloric Acid SCHEMBL6826939 | 0.64 | EGFR (0.67) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004112714-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-12-29 | — | — | WO | disclosed |